Publications by Xiaoxue Li | EPFL Graph Search

Related publications (5)

Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila

Bruno Lemaitre, Jean Philippe Boquete, Sveta Chakrabarti, Jan Paul Dudzic, Xiaoxue Li

The JAK/STAT pathway is a key signaling pathway in the regulation of development and immunity in metazoans. In contrast to the multiple combinatorial JAK/STAT pathways in mammals, only one canonical JAK/STAT pathway exists in Drosophila. It is activated by ...

Public Library of Science2016

Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow

Bruno Lemaitre, Xiaoxue Li

The gut must perform a dual role of protecting the host against toxins and pathogens while harboring mutualistic microbiota. Previous studies suggested that the NADPH oxidase Duox contributes to intestinal homeostasis in Drosophila by producing reactive ox ...

Elsevier BV2024

Transforming Growth Factor beta/Activin signaling in neurons increases susceptibility to starvation

Bruno Lemaitre, Xiaoxue Li, Wen Bin Chng

Animals rely on complex signaling network to mobilize its energy stores during starvation. We have previously shown that the sugar-responsive TGF beta/Activin pathway, activated through the TGF beta ligand Dawdle, plays a central role in shaping the post-p ...

2017

Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage

Bruno Lemaitre, Samuel Rommelaere, Xiaoxue Li

Animals require complex metabolic and physiological adaptations to maintain the function of vital organs in response to environmental stresses and infection. Here, we found that infection or injury in Drosophila induced the excretion of hemolymphatic lipid ...

2020

Autophagy as a Gatekeeper of Intestinal Homeostasis

Bruno Lemaitre, Xiaoxue Li

The control of gut homeostasis by autophagy in the context of host-microbiota relationship remains poorly understood. In this issue of Developmental Cell, Nagai et al. (2021) show that autophagy plays a crucial role in enterocytes to prevent the mis-regula ...

Cell Press - Elsevier2021