Publications by Constantin Richard Krüger

Related publications (6)

Structure and dynamics of deeply supercooled water

Water is the solvent that enables life, essential to every biological process and shaping our environment. Yet, it is the most anomalous liquid known to humankind. Many of these anomalous properties originate from the deeply supercooled regime. Unfortunate ...

EPFL2025

Electron diffraction of deeply supercooled water in no man’s land

Marcel Drabbels, Ulrich Lorenz, Gabriele Bongiovanni, Constantin Richard Krüger, Nathan Junior Mowry

A generally accepted understanding of the anomalous properties of water will only emerge if it becomes possible to systematically characterize water in the deeply supercooled regime, from where the anomalies appear to emanate. This has largely remained elu ...

Nature Research2023

Direct measurement of the critical cooling rate for the vitrification of water

Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Nathan Junior Mowry

The vitrification of aqueous solutions through rapid cooling is a remarkable achievement that launched the field of cryo-electron microscopy (cryo-EM) and has enabled the cryopreservation of biological specimens. For judging the feasibility of a vitrificat ...

2025

Shaped Laser Pulses for Microsecond Time-Resolved Cryo-EM: Outrunning Crystallization during Flash Melting

Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Nathan Junior Mowry

Water vitrifies if cooled at rates above 3 × 105 K/s. In contrast, when the resulting amorphous ice is flash heated, crystallization occurs even at a more than 10 times higher heating rate, as we have recently shown. This may present an issue for microseco ...

2024

Flash Melting Amorphous Ice

Marcel Drabbels, Ulrich Lorenz, Gabriele Bongiovanni, Constantin Richard Krüger, Nathan Junior Mowry

Water can be vitrified if it is cooled at high rates, which makes it possible to outrun crystallization in so-called no man’s land, a range of deeply supercooled temperatures where water crystallizes rapidly. Here, we study the reverse process in pure wate ...

2024

Sealed Samples for High-resolution, Microsecond Cryo-EM

Wyatt Abbott Curtis, Jakub Wenz, Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Sarah Victoria Barrass

Oxford University Press (OUP)2025