Publications by Harshit Gupta | EPFL Graph Search

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Optical diffraction tomography is an effective tool to estimate the refractive indices of unknown objects. It proceeds by solving an ill-posed inverse problem for which the wave equation governs the scattering events. The solution has traditionally been de ...

We present CryoGAN, a new paradigm for single-particle cryo-electron microscopy (cryo-EM) reconstruction based on unsupervised deep adversarial learning. In single-particle cryo-EM, the structure of a biomolecule needs to be reconstructed from a large set ...

We introduce a variational framework to learn the activation functions of deep neural networks. Our aim is to increase the capacity of the network while controlling an upper-bound of the actual Lipschitz constant of the input-output relation. To that end, ...

We propose a novel unsupervised deep-learning-based algorithm for dynamic magnetic resonance imaging (MRI) reconstruction. Dynamic MRI requires rapid data acquisition for the study of moving organs such as the heart. We introduce a generalized version of t ...

We develop an efficient computational solution to train deep neural networks (DNN) with free-form activation functions. To make the problem well-posed, we augment the cost functional of the DNN by adding an appropriate shape regularization: the sum of the ...

We present a theoretical analysis and comparison of the effect of

ℓ _{ 1 }

versus

ℓ _{ 2 }

regularization for the resolution of ill-posed linear inverse and/or compressed sensing problems. Our formulation covers the most general setting where the s ...

We propose a discretization method for continuous-domain linear inverse problems with multiple-order total-variation (TV) regularization. It is based on a recent result that proves that such inverse problems have sparse polynomial-spline solutions. Our met ...

We propose a deep-learning-based reconstruction method for cryo-electron microscopy (Cryo-EM) that can model multiple conformations of a nonrigid biomolecule in a standalone manner. Cryo-EM produces many noisy projections from separate instances of the sam ...

We study continuous-domain linear inverse problems with generalized total-variation (gTV) regularization, expressed in terms of a regularization operator L. It has recently been proved that such inverse problems have sparse spline solutions, with fewer jum ...

In this thesis, we propose new algorithms to solve inverse problems in the context of biomedical images. Due to ill-posedness, solving these problems require some prior knowledge of the statistics of the underlying images. The traditional algorithms, in th ...

Harshit Gupta

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Deep-learning projector for optical diffraction tomography

CryoGAN: A New Reconstruction Paradigm for Single-Particle Cryo-EM Via Deep Adversarial Learning

Deep Neural Networks With Trainable Activations and Controlled Lipschitz Constant

Time-Dependent Deep Image Prior for Dynamic MRI

Learning Activation Functions in Deep (Spline) Neural Networks

Representer Theorems for Sparsity-Promoting $ ℓ _{ 1 } $ Regularization

Solving Continuous-Domain Problems Exactly with Multiresolution B-Splines

Multi-CryoGAN: Reconstruction of Continuous Conformations in Cryo-EM Using Generative Adversarial Networks

B-Spline-Based Exact Discretization of Continuous-Domain Inverse Problems With Generalized TV Regularization

From Classical to Unsupervised-Deep-Learning Methods for Solving Inverse Problems in Imaging