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Constantin Tuleasca

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Related publications (106)

The annular closure device-panacea of lumbar disc herniation: how closed is closed enough for the intervertebral disc space?

Constantin Tuleasca

2021

Intraoperative Mri for the Microsurgical Resection of Meningiomas Close to Eloquent Areas or Dural Sinuses: Patient Series

Constantin Tuleasca

BACKGROUND Meningiomas are the most commonly encountered nonglial primary intracranial tumors. The authors report on the usefulness of intraoperative magnetic resonance imaging (iMRI) during microsurgical resection of meningiomas located close to eloquent ...

AMER ASSOC NEUROLOGICAL SURGEONS2021

Biologically effective dose and prediction of obliteration of unruptured arteriovenous malformations treated by upfront Gamma Knife radiosurgery: a series of 149 consecutive cases

Constantin Tuleasca

OBJECTIVE Arteriovenous malformations (AVMs) present no pathologic tissue, and radiation dose is confined in a clear targeted volume. The authors retrospectively evaluated the role of the biologically effective dose (BED) after Gamma Knife radiosurgery (GK ...

2021

Biologically effective dose correlates with linear tumor volume changes after upfront single-fraction stereotactic radiosurgery for vestibular schwannomas

Constantin Tuleasca

Vestibular schwannomas (VSs) are benign, slow-growing tumors. Management options include observation, surgery, and radiation. In this retrospective trial, we aimed at evaluating whether biologically effective dose (BED) plays a role in tumor volume changes ...

2021

Gamma Knife radiosurgery as salvage therapy for gangliogliomas after initial microsurgical resection

Constantin Tuleasca

Introduction: Gangliogliomas (GG) are considered WHO grade I rare tumors. While they commonly manifest as temporal lobe epilepsy, they can be located anywhere in the brain. Primary treatment is complete microsurgical resection. Remnant or recurrent GG can ...

2021

Biologically effective dose and the treatment of AVMs Response

Constantin Tuleasca

2021

Surgical management of anterior clinoidal meningiomas: consensus statement on behalf of the EANS skull base section

Constantin Tuleasca

Background The optimal management of clinoidal meningiomas (CMs) continues to be debated. Methods We constituted a task force comprising the members of the EANS skull base committee along with international experts to derive recommendations for the managem ...

2021

Gamma Knife radiosurgery for acromegaly: Evaluating the role of the biological effective dose associated with endocrine remission in a series of 42 consecutive cases

Constantin Tuleasca

Introduction Stereotactic radiosurgery (SRS) is a valuable treatment option for persistent and/or recurrent acromegaly secondary to growth hormone (GH) secreting pituitary adenoma (PA). Here, we assess the role of biological effective dose (BED) received b ...

2021

The Brain Connectome after Gamma Knife Radiosurgery of the Ventro-Intermediate Nucleus for Tremor: Marseille-Lausanne Radiobiology Study Protocol

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Constantin Tuleasca

Essential tremor (ET) is the most common movement disorder. Deep brain stimulation is the current gold standard for drug-resistant tremor, followed by radiofrequency lesioning. Stereotactic radiosurgery by Gamma Knife (GK) is considered as a minimally inva ...

2021

Impact of combined use of intraoperative MRI and awake microsurgical resection on patients with gliomas: a systematic review and meta-analysis

Constantin Tuleasca

Microsurgical resection of primary brain tumors located within or near eloquent areas is challenging. Primary aim is to preserve neurological function, while maximizing the extent of resection (EOR), to optimize long-term neurooncological outcomes and qual ...

2021

Improved susceptibility-weighted imaging for high contrast and resolution thalamic nuclei mapping at 7T

Meritxell Bach Cuadra, Elena Najdenovska, José Pedro Rebelo Ferreira Marques, Frédéric Gretsch, João Pedro Forjaco Jorge, Daniel Gallichan, Constantin Tuleasca

Purpose The thalamus is an important brain structure and neurosurgical target, but its constituting nuclei are challenging to image non-invasively. Recently, susceptibility-weighted imaging (SWI) at ultra-high field has shown promising capabilities for tha ...

Wiley2020

TbCAPs: A toolbox for co-activation pattern analysis

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Eva Blondiaux, Constantin Tuleasca, Gwladys Rey, Julian Gaviria, Herberto Dhanis Pedro De Barros Camacho, Baptiste Gauthier, Lukasz Dawid Smigielski, Elenor Morgenroth, Farnaz Delavari

Functional magnetic resonance imaging provides rich spatio-temporal data of human brain activity during task and rest. Many recent efforts have focussed on characterising dynamics of brain activity. One notable instance is co-activation pattern (CAP) analy ...

2020

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Olivier Michielin, Alexandre Wicky, Krisztian Homicsko, Constantin Tuleasca, Filipe Amândio Brandão Sanches Vong Martins

Background Evidence pointing to a synergistic effect of stereotactic radiosurgery (SRS) with concurrent immunotherapy or targeted therapy in patients with melanoma brain metastases (BM) is increasing. We aimed to analyze the effect on overall survival (OS) ...

SPRINGER2020

Establishment of a Therapeutic Ratio for Gamma Knife Radiosurgery of Trigeminal Neuralgia: The Critical Importance of Biologically Effective Dose Versus Physical Dose

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

OBJECTIVE: How variations of treatment time affect the safety and efficacy of Gamma Knife (GK) radiosurgery is a matter of considerable debate. With the relative simplicity of treatment planning for trigeminal neuralgia (TN), this question has been address ...

2020

Surgical management for large vestibular schwannomas: a systematic review, meta-analysis, and consensus statement on behalf of the EANS skull base section

Constantin Tuleasca

Background and objective The optimal management of large vestibular schwannomas continues to be debated. We constituted a task force comprising the members of the EANS skull base committee along with international experts to derive recommendations for the ...

2020

Graph theory analysis of resting-state functional magnetic resonance imaging in essential tremor

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Constantin Tuleasca

Wiley2020

Impact of the skull contour definition on Leksell Gamma Knife(R)Icon (TM) radiosurgery treatment planning

Constantin Tuleasca

Introduction The Gamma Knife(R)planning software (TMR 10, Elekta Instruments, AB, Sweden) affords two ways of defining the skull volume, the "historical" one using manual measurements (still perform in some centers) and the new one using image-based skull ...

2020

Multimodal management for benign skull base meningiomas

Constantin Tuleasca

2020

Microsurgical resection of a radicular hemangioblastoma with subarachnoid hemorrhage: how I do it

Constantin Tuleasca

Background Hemangioblastomas (HBL) are benign tumors occurring sporadically or associated with Von Hippel-Lindau syndrome (VHL). Method We present the pre-, per-, and postoperative course of a rare case with radicular HBL presenting with subarachnoid hemor ...

2020

Transsphenoidal resection for pituitary adenoma in elderly versus younger patients: a systematic review and meta-analysis

Constantin Tuleasca

Introduction Pituitary adenomas (PA) are common intracranial tumors. In the context of the aging of the population, the question is whether postsurgical outcomes are comparable to the younger ones. The primary objective of the present study was to review p ...

2020

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