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Ardemis Anoush Boghossian

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Related publications (35)

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Noncovalent Protein and Peptide Functionalization of Single-Walled Carbon Nanotubes for Biodelivery and Optical Sensing Applications

Ardemis Anoush Boghossian, Alessandra Antonucci, Justyna Kupis-Rozmyslowicz

The exquisite structural and optical characteristics of single-walled carbon nanotubes (SWCNTs), combined with the tunable specificities of proteins and peptides, can be exploited to strongly benefit technologies with applications in fields ranging from bi ...

Amer Chemical Soc2017

Polydopamine-coated photoautotrophic bacteria for improving extracellular electron transfer in living photovoltaics

Ardemis Anoush Boghossian, Melania Reggente, Hanxuan Wang, Charlotte Elisabeth Marie Roullier, Mohammed Mouhib

Living photovoltaics are microbial electrochemical devices that use whole cell–electrode interactions to convert solar energy to electricity. The bottleneck in these technologies is the limited electron transfer between the microbe and the electrode surfac ...

2024

Design of Optimized PEDOT‐Based Electrodes for Enhancing Performance of Living Photovoltaics Based on Phototropic Bacteria

Ardemis Anoush Boghossian, Alessandra Antonucci, Melania Reggente

Living photovoltaics represent a growing class of microbial devices that are based on whole cell–electrode interactions. The limited charge transfer at the cell–electrode interface represents a significant bottleneck in realizing an efficient technology. T ...

Wiley2020

Non-covalent Methods of Engineering Optical Sensors Based on Single-Walled Carbon Nanotubes

Ardemis Anoush Boghossian, Alice Judith Gillen

Optical sensors based on single-walled carbon nanotubes (SWCNTs) demonstrate tradeoffs that limit their use in in vivo and in vitro environments. Sensor characteristics are primarily governed by the non-covalent wrapping used to suspend the hydrophobic SWC ...

2019

Engineering the Selectivity of the DNA-SWCNT Sensor

Ardemis Anoush Boghossian, Alessandra Antonucci, Justyna Kupis-Rozmyslowicz

Single-walled carbon nanotubes (SWCNTs) demonstrate a unique combination of optical, chemical, and physical properties that render them suitable for a variety of sensing applications. Their photostable near-infrared (nIR) fluorescence emissions are highly ...

Electrochemical Soc Inc2016

Bioengineering a glucose oxidase nanosensor for near-infrared continuous glucose monitoring

Ardemis Anoush Boghossian, Vitalijs Zubkovs, Nils Schürgers, Hanxuan Wang

Single-walled carbon nanotubes (SWCNTs) emit photostable near-infrared fluorescence that is conducive for optical glucose monitoring. Such SWCNT-based optical sensors often require the immobilization of proteins that can confer glucose selectivity and reac ...

2022

Prediction of mycotoxin response of DNA-wrapped nanotube sensor with machine learning

Ardemis Anoush Boghossian, Sara Behjati, Sayyed Hashem Sajjadi, Yahya Rabbani

DNA-wrapped single-walled carbon nanotubes (DNA-SWCNTs) have demonstrated great versatility as optical sensors. SWCNTs emit a near-infrared fluorescence that is responsive to the slightest changes in their environment, enabling the creation of sensors that ...

2023

A synthetic biology approach to engineering living photovoltaics

Ardemis Anoush Boghossian, Nils Schürgers

The ability to electronically interface living cells with electron accepting scaffolds is crucial for the development of next-generation biophotovoltaic technologies. Although recent studies have focused on engineering synthetic interfaces that can maximiz ...

Royal Soc Chemistry2017

Transport and programmed release of nanoscale cargo from cells by using NETosis

Ardemis Anoush Boghossian, Alice Judith Gillen, Alessandra Antonucci

Cells can take up nanoscale materials, which has important implications for understanding cellular functions, biocompatibility as well as biomedical applications. Controlled uptake, transport and triggered release of nanoscale cargo is one of the great cha ...

ROYAL SOC CHEMISTRY2020

Living on the Edge: Re-shaping the Interface of Synthetic Biology and Nanotechnology

Ardemis Anoush Boghossian, Shang-Jung Wu

A new team of researchers at EPFL is taking an 'anti-disciplinary' approach to creating optical devices. These devices take advantage of the synergy in tuning both nano- and bio-material properties, coupling 'the advantages of two growing, albeit tradition ...

Schweizerische Chemische Gesellschaft2016

Cation Pretreatment Enables the Saline Stability of a Near-Infrared Sensor for Dopamine

Ardemis Anoush Boghossian, Hanxuan Wang

Single-walled carbon nanotubes (SWCNTs) are wrapped with single-stranded DNA (ssDNA) to create near-infrared (NIR-II) fluorescent sensors for diverse analytes. However, the interaction between the negatively charged backbone of ssDNA and cations in biologi ...

2025

Applications of Nanoparticles for Reactive Oxygen Species (ROS) Scavenging in Photosynthetic Systems

Ardemis Anoush Boghossian

Under aerobic conditions, excessive illumination results in the photogeneration of reactive oxygen species (ROS) responsible for protein damage and photo-inhibition during photosynthesis. We explore the effects of nanoceria (NC), a regenerative ROS scaveng ...

The Electrochemical Society2015

A molecular tool and use thereof in a label-free method for detecting a target nucleic acid in a sample

Ardemis Anoush Boghossian, Alice Judith Gillen

A molecular tool and a label-free method useful for detecting a target nucleic acid in a sample are disclosed, the molecular tool comprising a substrate comprising or consisting of an optical material; a first polymeric molecule, selected from nucleic acid ...

2022

Analytical Approaches for Monitoring DNA–Protein Interactions

Ardemis Anoush Boghossian, Shang-Jung Wu

DNA–protein interactions play a critical role in cellular regulation. We herein review existing analytical methods for investigating these interactions, highlighting methods such as chromatin immunoprecipitation and yeast-one-hybrid that are used to identi ...

2019

Bioengineering DNA for Carbon Nanotube Sensors

Ardemis Anoush Boghossian, Sara Behjati, Yahya Rabbani

Single-walled carbon nanotubes (SWCNTs) generate near-infrared fluorescence that is useful for biomedical and environmental optical sensing. They can be colloidally suspended by π-electron-rich biopolymers like DNA that self-assemble onto their surfaces. T ...

World Scientific2025

Biotechnology Applications of Nanocarbons in Plant and Algal Systems

Ardemis Anoush Boghossian, Alice Judith Gillen, Alessandra Antonucci

The unique combination of structural, optical, and electronic properties of nanocarbons (NCs) has made these materials particularly attractive for various applications in biotechnology and biomedicine, ranging from sensing, gene-delivery, bioimaging and th ...

Royal Society of Chemistry2021

Micropreparative Gel Electrophoresis for Purification of Nanoscale Bioconjugates

Ardemis Anoush Boghossian, Yahya Rabbani, Shang-Jung Wu, Vitalijs Zubkovs, Sayyed Hashem Sajjadi

Conventional techniques for purifying macromolecular conjugates often require complex and costly installments that are inaccessible to most laboratories. In this work, we develop a one-step micropreparative method based on a trilayered polyacrylamide gel e ...

2024

Site-Specific Protein Conjugation onto Fluorescent Single-Walled Carbon Nanotubes

Ardemis Anoush Boghossian, Vitalijs Zubkovs, Shang-Jung Wu, Nils Schürgers

Semiconducting single-walled carbon nanotubes (SWCNTs) are among the few photostable optical emitters that are ideal for sensing, imaging, drug delivery, and monitoring of protein activity. These applications often require strategies for immobilizing prote ...

2020

Xeno Nucleic Acid Nanosensors for Enhanced Stability Against Ion-Induced Perturbations

Ardemis Anoush Boghossian, Carlo Gigli, Alice Judith Gillen, Justyna Kupis-Rozmyslowicz

The omnipresence of salts in biofluids creates a pervasive challenge in designing sensors suitable for in vivo applications. Fluctuations in ion concentrations have been shown to affect the sensitivity and selectivity of optical sensors based on single-wal ...

2018

Enhancing bioelectricity generation in microbial fuel cells and biophotovoltaics using nanomaterials

Ardemis Anoush Boghossian, Alice Judith Gillen, Alessandra Antonucci, Melania Reggente, Mohammed Mouhib, Amirmostafa Amirjani

Microbial fuel cells and biophotovoltaics represent promising technologies for green bioelectricity generation. However, these devices suffer from low durability and efficiency that stem from their reliance on living organisms to act as catalysts. Such lim ...

2019