Publications by Francesco Piraino

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The interplay between genetic ancestry and biological sex is increasingly recognized as a critical factor influencing health outcomes, treatment efficacy, and drug toxicity. Current research highlights significant disparities in disease susceptibility and ...

The intricate process of wound healing involves activation of biological pathways that work in concert to regenerate a tissue microenvironment consisting of cells and external cellular matrix (ECM) with enzymes, cytokines, and growth factors. Distinct stag ...

Microfluidic diagnostic devices have the potential to transform the practice of medicine. We engineered a multiplexed digital-analog microfluidic platform for the rapid and highly sensitive detection of 3-4 biomarkers in quadruplicate in 16 independent and ...

High failure rates of the current drug development process are driving exemplary changes toward methodologies centered on human disease in-vitro modeling. Organoids are self-organized tissue sub-units resembling their organ of origin and are widely acknowl ...

The invention relates to a microfluidic device for performing digital analysis of a whole blood sample. ...

Francesco Piraino

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Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies

A Digital-Analog Microfluidic Platform for Patient-Centric Multiplexed Biomarker Diagnostics of Ultralow Volume Samples

Organoid models: the future companions of personalized drug development

New Biomaterials in Drug Delivery and Wound Care

A system, device and method for multiplexed biomarker diagnostics of ultra-low volume whole blood samples