Yann Christophe Sprunger

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Understanding the biochemical relationship between serum and dermal interstitial fluid (dISF) is critical for advancing minimally invasive diagnostics with wearables and point of care devices focusing on most relevant biomarkers accessible in the ISF. This ...

Accurately measuring cortisol levels is crucial for diagnosing and managing stress-related conditions. Among all biofluids containing cortisol, Interstitial fluid (ISF) offers distinct advantages such as stable pH, continuous extraction, and minimal contam ...

In this paper we demonstrate ultra-high sensitivity silicon nanowires pH and protein sensing on the same Silicon nanowire array platform by using a constant current method and monitoring the drain voltage as function of analyte concentration. The injected ...

In this paper, we propose a novel approach to utilize silicon nanowires as high-sensitivity pH sensors. Our approach works based on fixing the current bias of silicon nanowires Ion Sensitive Field Effect Transistors (ISFETs) and monitor the resulting drain ...

The rising cost of healthcare, driven by ageing populations and chronic disease prevalence, places mounting pressure on health systems. This trend risks prioritizing cost-efficiency over clinical value. In response, healthcare models are evolving toward value-based care, outcome-driven reimbursement, hospital-at-home frameworks, and data-informed prevention strategiesâ all aiming to optimize resources and improve patient outcomes. In this context, wearable biosensors emerge as key enablers. By enabling co

Yann Christophe Sprunger

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Bridging Blood and Skin: Biomarker Profiling in Dermal Interstitial Fluid (dISF) for Minimally Invasive Diagnostics

AC-Driven Aptamer-Decorated Graphene FET for Cortisol Detection

Ultra-High Sensitivity Silicon Nanowire Array Biosensor Based on a Constant-Current Method for Continuous Real-Time pH and Protein Monitoring in Interstitial Fluid

pH Quantification in Human Dermal Interstitial Fluid Using Ultra-Thin SOI Silicon Nanowire ISFETs and a High-Sensitivity Constant-Current Approach

Biomarkers in Interstitial Fluid: From Screening to Sensor Development