Publications by Yifan Li | EPFL Graph Search

Related publications (11)

Synthesis of Alkynylated Heterocycles by Direct C-H Alkynylation or Domino Alkynylation Reactions

Heterocycles are important compounds in organic chemistry. To introduce functional groups on heterocycles or synthesize functionalized heterocycles stays a hot topic of research. Among all the functional groups, alkynes attracted a lot of attention not onl ...

EPFL2016

Gold-Catalyzed Alkynylation: Acetylene-Transfer instead of Functionalization

Jérôme Waser, Jonathan Brand, Yifan Li

Over the last fifteen years, gold has been raised from the status of an inert noble metal to one of the most-often-used catalysts in synthetic chemistry. The functionalization of the triple bond of alkynes has been especially successful in this respect. In ...

Wiley-V C H Verlag Gmbh2013

Two-dimensional nanochannel membranes for molecular and ionic separations

Shaoyu Wang, Guangwei He, Yifan Li

Two-dimensional (2D) nanosheets have emerged as promising functional materials owing to their atomic thickness and unique physical/chemical properties. By using 2D nanosheets as building blocks, diverse kinds of two-dimensional nanochannel membranes (2DNCM ...

Royal Society of Chemistry2020

Cyclic Hypervalent Iodine Reagents for Atom-Transfer Reactions: Beyond Trifluoromethylation

Jérôme Waser, Yifan Li, Durga Prasada Rao Hari, Maria Victoria Vita

Hypervalent iodine compounds are privileged reagents in organic synthesis because of their exceptional reactivity. Among these compounds, cyclic derivatives stand apart because of their enhanced stability. They have been widely used as oxidants, but their ...

Wiley-Blackwell2016

Platinum-Catalyzed Domino Reactionwith Benziodoxole Reagents for Accessing Benzene-Alkynylated Indoles

Jérôme Waser, Yifan Li

Indoles are omnipresent in natural products, bioactive molecules, and organic materials. Consequently, their synthesis or functionalization are important fields of research in organic chemistry. Most works focus on installation or modification of the pyrro ...

Wiley-Blackwell2015

Zinc-gold cooperative catalysis for the direct alkynylation of benzofurans

Jérôme Waser, Yifan Li

The direct alkynylation of benzofurans was achieved for the first time using the hypervalent iodine reagent 1-[(triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX) based on the cooperative effect between a gold catalyst and a zinc Lewis acid. H ...

2013

Heterotetracenes: Flexible Synthesis and in Silico Assessment of the Hole Transport Properties

Jérôme Waser, Anne-Clémence Corminboeuf, Kevin Sivula, Xavier Adrian Jeanbourquin, Ganna Gryn'ova, Yifan Li, Felipe Andres Saenz Padilla

Thienoacenes and furoacenes are among the most frequent molecular units found in organic materials. The efficient synthesis of morphologically different heteroacenes and the rapid determination of their solid-state and electronic properties are still chall ...

2017

Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism

Jérôme Waser, Paola Caramenti, Yifan Li

Gold-catalyzed domino processes constitute a useful alternative to C-H functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynyl ...

2017

New Binding Sites, New Opportunities for GPCR Drug Discovery

Horst Arthur Vogel, Yen-Huan Li, Shuguang Yuan, Yifan Li, Thamani Dahoun

Many central biological events rely on protein-ligand interactions. The identification and characterization of protein-binding sites for ligands are crucial for the understanding of functions of both endogenous ligands and synthetic drug molecules. G prote ...

ELSEVIER SCIENCE LONDON2019

Taming Hypervalent Bonds and Strained Rings for Catalysis and Synthesis

Jérôme Waser, Florian Patrick Marie Daniel De la Barre De Nanteuil, Reto Frei, Yifan Li, Maria Victoria Vita, Sophie Lucie Racine, Eloísa Sofía Serrano Robledo

Improving the synthesis of complex organic molecules is essential for progress in many fields such as medicine, agrochemicals or materials. Since 2007, our laboratory has been focusing on the development of non-classical bond disconnections based on the us ...

2014

Gold-Catalyzed Regioselective Synthesis of 2- and 3-Alkynyl Furans

Jérôme Waser, Jonathan Brand, Yifan Li

Wiley-VCH Verlag GmbH2013