Publications by Fabio Mario Spiga

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In the framework of bioanalytics and multiple array detection, we developed a fully portable and low-cost detection system based on Localized Surface Plasmon Resonance (LSPR) in a transmission configuration (T-LSPR). The transmission approach is suitable t ...

To address limitations in the production of DNA aptamers against small molecules, we introduce a DNA-based capture-SELEX (systematic evolution of ligands by exponential enrichment) protocol with long and continuous randomized library for more flexibility, ...

A more specific and intense signal is desirable for most kinds of biosensors for biomedical or environmental applications, and it is especially so for label-free biosensors. In this paper, we show that hybridization chain reaction (HCR) can be exploited fo ...

Download Citation Email Print Request Permissions Save to Project Electronic biochips are defined by the merge of integrated electronics, containing diverse sensors, with reaction solution and sample hold in reaction chamber(s). Based on their overall stru ...

In order to improve the efficacy and safety of treatments, drug dosage needs to be adjusted to the actual needs of each patient in a truly personalized medicine approach. Key for widespread dosage adjustment is the availability of point-of-care devices abl ...

More than 40 years after the invention of semiconductor pH microtransducers known as ISFETs, this transistor-based technology may revolutionize quantitative PCR. ...

Fabio Mario Spiga

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A Portable Setup for Molecular Detection by Transmission LSPR

More DNA–Aptamers for Small Drugs: A Capture–SELEX Coupled with Surface Plasmon Resonance and High-Throughput Sequencing

Hybridization chain reaction performed on a metal surface as a means of signal amplification in SPR and electrochemical biosensors

Digital approaches in Electronic biochips

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

Another transistor-based revolution: on-chip qPCR