Publications by Lorenzo Mari | EPFL Graph Search

Related publications (46)

The role of aquatic reservoir fluctuations in long-term cholera patterns

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

We propose and analyze an important extension of standard cholera epidemiological models, explicitly accounting for fluctuations of water availability to the human community under study. The seasonality of water input in the reservoir drives the variation ...

2012

Spread of proliferative kidney disease in fish along stream networks: A spatial metacommunity framework

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro

Proliferative kidney disease (PKD) is a high-mortality pathology that critically affects freshwater salmonid populations. Infection is caused by the endoparasitic myxozoan Tetracapsuloides bryosalmonae, which exploits freshwater bryozoans as primary hosts. ...

2018

Reassessment of the 2010-2011 Haiti cholera outbreak and rainfall-driven multiseason projections

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari, Lorenzo Righetto

Mathematical models can provide key insights into the course of an ongoing epidemic, potentially aiding real-time emergency management in allocating health care resources and by anticipating the impact of alternative interventions. We study the ex post rel ...

2012

Hydroclimatology of dual-peak annual cholera incidence: Insights from a spatially explicit model

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

Cholera incidence in some regions of the Indian subcontinent may exhibit two annual peaks although the main environmental drivers that have been linked to the disease (e.g., sea surface temperature, zooplankton abundance, river discharge) peak once per yea ...

2012

Prediction of the spatial evolution and effects of control measures for the unfolding Haiti cholera outbreak

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari, Lorenzo Righetto

Here we propose spatially explicit predictions of the residual progression of the current Haiti cholera outbreak accounting for the dynamics of susceptible and infected individuals within different local human communities, and for the redistribution among ...

American Geophysical Union2011

A Theoretical Analysis of the Geography of Schistosomiasis in Burkina Faso Highlights the Roles of Human Mobility and Water Resources Development in Disease Transmission

Jean-Marc Fröhlich, Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Francisco Javier Perez Saez, Theophile Mande

We study the geography of schistosomiasis across Burkina Faso by means of a spatially explicit model of water-based disease dynamics. The model quantitatively addresses the geographic stratification of disease burden in a novel framework by explicitly acco ...

Public Library of Science2015

Biophysical controls on cluster dynamics and architectural differentiation of microbial biofilms in contrasting flow environments

Andrea Rinaldo, Tom Ian Battin, Enrico Bertuzzo, Lorenzo Mari, Samir Suweis

Ecology, with a traditional focus on plants and animals, seeks to understand the mechanisms underlying structure and dynamics of communities. In microbial ecology, the focus is changing from planktonic communities to attached biofilms that dominate microbi ...

Wiley-Blackwell2013

Hydrologic controls and anthropogenic drivers of the zebra mussel invasion of the Mississippi-Missouri river system

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari

We propose a novel ecohydrological model for the invasion of inland waters by the zebra mussel Dreissena polymorpha and test it against field data gathered within the Mississippi-Missouri river system in North America. This biological invasion poses major ...

American Geophysical Union2011

Light and hydrologic variability as drivers of stream biofilm dynamics in a flume experiment

Andrea Rinaldo, Tom Ian Battin, Enrico Bertuzzo, Lorenzo Mari, Serena Ceola

We run a comparative study of the results of flume experiments and several dynamic models reproducing the effects of streamflow variability on biofilm (i.e. periphyton) temporal dynamics. During the experiment, two contrasting flow regimes, characterised b ...

Wiley-Blackwell2014

Generalized reproduction numbers and the prediction of patterns in waterborne disease

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

Understanding, predicting, and controlling outbreaks of waterborne diseases are crucial goals of public health policies, but pose challenging problems because infection patterns are influenced by spatial structure and temporal asynchrony. Although explicit ...

Natl Acad Sciences2012

Spatial effects on species persistence and implications for biodiversity

Andrea Rinaldo, Enrico Bertuzzo, Amos Maritan, Lorenzo Mari, Samir Suweis

Natural ecosystems are characterized by striking diversity of form and functions and yet exhibit deep symmetries emerging across scales of space, time, and organizational complexity. Species-area relationships and species-abundance distributions are exampl ...

2011

On the role of human mobility in the spread of cholera epidemics: towards an epidemiological movement ecology

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which otherwise primarily propagate through hydrologically controlled ecological corridors. We rely on a recent mechanistic, field-data validated, spatial ...

Wiley-Blackwell2012

Optimal control of the spatial allocation of COVID-19 vaccines: Italy as a case study

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Damiano Pasetto, Joseph Chadi Benoit Lemaitre

While campaigns of vaccination against SARS-CoV-2 are underway across the world, communities face the challenge of a fair and effective distribution of a limited supply of doses. Current vaccine allocation strategies are based on criteria such as age or ri ...

2022

Spatially Explicit Conditions for Waterborne Pathogen Invasion

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

Waterborne pathogens cause many possibly lethal human diseases. We derive the condition for pathogen invasion and subsequent disease outbreak in a territory with specific, space-inhomogeneous characteristics (hydrological, ecological, demographic, and epid ...

Univ Chicago Press2013

Conditions for transient epidemics of waterborne disease in spatially explicit systems

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari

Waterborne diseases are a diverse family of infections transmitted through ingestion of-or contact with-water infested with pathogens. Outbreaks of waterborne infections often show well-defined spatial signatures that are typically linked to local eco-epid ...

2019

On species persistence-time distributions

Andrea Rinaldo, Enrico Bertuzzo, Amos Maritan, Lorenzo Mari, Samir Suweis

We present new theoretical and empirical results on the probability distributions of species persistence times in natural ecosystems. Persistence times, defined as the timespans occurring between species' colonization and local extinction in a given geogra ...

Elsevier2012

Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro

Proliferative kidney disease (PKD) is a major threat to wild and farmed salmonid populations because of its lethal effect at high water temperatures. Its causative agent, the myxozoan Tetracapsuloides bryosalmonae, has a complex lifecycle exploiting freshw ...

National Academy of Sciences2017

A generalized definition of reactivity for ecological systems and the problem of transient species dynamics

Andrea Rinaldo, Lorenzo Mari

Perturbations to an ecosystem's steady state can trigger transient responses of great ecological relevance. Asymptotic stability determines whether a generic perturbation will fade out in the long run, but falls short of characterizing the dynamics imme ...

Wiley2017

An epidemiological model for proliferative kidney disease in salmonid populations

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro

Background: Proliferative kidney disease (PKD) affects salmonid populations in European and North-American rivers. It is caused by the endoparasitic myxozoan Tetracapsuloides bryosalmonae, which exploits freshwater bryozoans and salmonids as hosts. Inciden ...

Biomed Central Ltd2016

Epidemicity indices and reproduction numbers from infectious disease data in connected human populations

Andrea Rinaldo, Lorenzo Mari, Cristiano Trevisin

We focus on distinctive data-driven measures of the fate of ongoing epidemics. The relevance of our pursuit is suggested by recent results proving that the short-term temporal evolution of infection spread is described by an epidemicity index related to th ...

2024