Publications by Marco Stenta | EPFL Graph Search

Related publications (8)

Reaction Mechanism and Catalytic Fingerprint of Allantoin Racemase

Matteo Dal Peraro, Marco Stenta, Matteo Thomas Degiacomi, Thomas Lemmin, Christophe Bovigny

The stereospecific oxidative decomposition of urate into allantoin is the core of purine catabolism in many organisms. The spontaneous decomposition of upstream intermediates and the nonenzymatic racemization of allantoin lead to an accumulation of (R)-all ...

Amer Chemical Soc2014

Functional Dissection of Intersubunit Interactions in the EspR Virulence Regulator of Mycobacterium tuberculosis

Stewart Cole, Giovanni Dietler, Matteo Dal Peraro, Florence Pojer, Marco Stenta, Aleksandre Japaridze, Benjamin Blasco

The nucleoid-associated protein EspR, a chromosome organizer, has pleiotropic effects on expression of genes associated with cell wall function and pathogenesis in Mycobacterium tuberculosis. In particular, EspR binds to several sites upstream of the espAC ...

American Society for Microbiology2014

Length control of the injectisome needle requires only one molecule of Yop secretion protein P (YscP)

Matteo Dal Peraro, Marco Stenta, Lisa Christina Metzger

The needle length of the Yersinia spp. injectisome is determined by Yop secretion protein P (YscP), an early substrate of the injectisome itself. There is a linear correlation between the length of YscP and the length of the needle, suggesting that YscP ac ...

National Academy of Sciences2010

In situ structural analysis of the Yersinia enterocolitica injectisome

Matteo Dal Peraro, Henning Paul-Julius Stahlberg, Marco Stenta, Matteo Thomas Degiacomi

Injectisomes are multi-protein transmembrane machines allowing pathogenic bacteria to inject effector proteins into eukaryotic host cells, a process called type III secretion. Here we present the first three-dimensional structure of Yersinia enterocolitica ...

Elife Sciences Publications Ltd2013

TAL Effectors Specificity Stems from Negative Discrimination

Matteo Dal Peraro, Marco Stenta

Transcription Activator-Like (TAL) effectors are DNA-binding proteins secreted by phytopathogenic bacteria that interfere with native cellular functions by binding to plant DNA promoters. The key element of their architecture is a domain of tandem-repeats ...

Public Library of Science2013

Molecular Simulations Highlight the Role of Metals in Catalysis and Inhibition of Type II Topoisomerase

Matteo Dal Peraro, Marco Stenta, Andrea Cavalli

Type II topoisomerase (topoII) is a metalloenzyme targeted by clinical antibiotics and anticancer agents. Here, we integrate existing structural data with molecular simulation and propose a model for the yet uncharacterized structure of the reactant state ...

Amer Chemical Soc2013

Dynamics of catalytic metals during DNA cleavage in type II topoisomerase

Matteo Dal Peraro, Marco Stenta, Giulia Palermo, Andrea Cavalli

Amer Chemical Soc2013

Uncommon 1,2-Migration of a Nitro Group Within a beta-Nitrostyryl Moiety: Synthetic Scope and Mechanistic Details

Marco Stenta

The unusual migration of a nitro group from the - to the -position of a -aryl--nitroethenyl moiety, following a nitrocyclopropane to isoxazoline N-oxide isomerization, has been studied from a mechanistic and synthetic points of view. As a result, two serie ...

Wiley-V C H Verlag Gmbh2013