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Cristina Granziera

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Related publications (61)

Page 2 of 4

Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Leila Cammoun, Djalel Eddine Meskaldji, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

There is growing interest in understanding the role of the non-injured contra-lateral hemisphere in stroke recovery. In the experimental field, histological evidence has been reported that structural changes occur in the contra-lateral connectivity and cir ...

2011

Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits

Jean-Philippe Thiran, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Gloria Menegaz, David Paul Roger Romascano, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin

Conventional magnetic resonance imaging (MRI) of patients with multiple sclerosis provides only limited insights into the nature of brain tissue damage with modest clinical-radiological correlations. In this study, quantitative and semi-quantitative MRI te ...

2014

A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients

Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Bénédicte Marie Maréchal, Muhamed Barakovic, Ricardo Alberto Corredor Jerez, Lester Melie Garcia

BackgroundDetecting new and enlarged lesions in multiple sclerosis (MS) patients is needed to determine their disease activity. LeMan-PV is a software embedded in the scanner reconstruction system of one vendor, which automatically assesses new and enlarge ...

WILEY2023

Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI

Wietske Van der Zwaag, Cristina Granziera, Gunnar Krüger, Guillaume Bonnier, Kieran O'Brien, Yohan Boillat

Although having a relatively homogeneous cytoarchitectonic organization, the cerebellar cortex is a heterogeneous region characterized by different amounts of myelin, iron and protein expression profiles. In this study, we used quantitative T1 and T2* mapp ...

2018

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Meritxell Bach Cuadra, Alessandro Daducci, Reto Meuli, Gunnar Krüger, Bénédicte Marie Maréchal, Cristina Granziera, Alexis Roche, Delphine Ribes Lemay, Daniel Andreas Schmitter

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Proceedings of 23rd International Society for Magnetic Resonance in Medicine (ISMRM) Conference2014

In-vivo magnetic resonance imaging of the structural core of the Papez circuit in humans

Reto Meuli, Cristina Granziera, Nouchine Hadjikhani

Papez circuit is one of the major pathways of the limbic system, and it is involved in the control of memory and emotion. Structural and functional alterations have been reported in psychiatric, neurodegenerative, and epileptic diseases. Despite the clinic ...

2011

Magnetization transfer-based 3D visualization of foot peripheral nerves

Cristina Granziera, Gunnar Krüger, Bénédicte Marie Maréchal, Giulio Gambarota

PURPOSE: To investigate magnetization transfer (MT) effects as a new source of contrast for imaging and tracking of peripheral foot nerves. MATERIALS AND METHODS: Two sets of 3D spoiled gradient-echo images acquired with and without a saturation pulse were ...

Wiley-Blackwell2013

Shallow vs deep learning architectures for white matter lesion segmentation in the early stages of multiple sclerosis

Jean-Philippe Thiran, Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Jonas Richiardi, Francesco La Rosa

In this work, we present a comparison of a shallow and a deep learning architecture for the automated segmentation of white matter lesions in MR images of multiple sclerosis patients. In particular, we train and test both methods on early stage disease pat ...

Springer2018

Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues

Jean-Philippe Thiran, Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa

The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to misdiagnosis, which remains an issue in present-day clinical practice. In addition, conventional biomarkers only moderately correlate with MS disease progres ...

ELSEVIER SCI LTD2022

An evaluation of volume-based morphometry for prediction of mild cognitive impairment and Alzheimer's disease

Reto Meuli, Meritxell Bach Cuadra, Alessandro Daducci, Gunnar Krüger, Cristina Granziera, Bénédicte Marie Maréchal, Daniel Andreas Schmitter, Alexis Roche, Delphine Ribes Lemay

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer’s disease (AD) related brain atrophy and to enable fairly accurate automated classification of AD patients, mild cognitive impaired patients (MCI) and e ...

Elsevier2015

Cerebellar Cortical Layers: In Vivo Visualization with Structural High-Field-Strength MR Imaging

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Wietske Van der Zwaag, Cristina Granziera, Gunnar Krüger

Purpose: To perform in vivo imaging of the cerebellum with an in-plane resolution of 120 mm to observe its cortical granular and molecular layers by taking advantage of the high signal-to-noise ratio and the increased magnetic susceptibility-related contra ...

2010

Diffusion Spectrum Imaging Shows the Structural Basis of Functional Cerebellar Circuits in the Human Cerebellum In Vivo

Reto Meuli, Cristina Granziera, Nouchine Hadjikhani

Background: The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits. Identifying the structural bases of cerebellar neuronal networks in humans in vi ...

2009

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Jonas Richiardi, Gloria Menegaz, David Paul Roger Romascano, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

2014

Towards a diffusion image processing validation and accuracy prediction framework

Jean-Philippe Thiran, Meritxell Bach Cuadra, Alessandro Daducci, Cristina Granziera, Gloria Menegaz, Alia Lemkaddem

Validation is the main bottleneck preventing the adoption of many medical image processing algorithms in the clinical practice. In the classical approach, a-posteriori analysis is performed based on some objective metrics. In this work, a different approac ...

2011

FID-guided retrospective motion correction based on autofocusing

Rolf Gruetter, Tobias Kober, Gunnar Krüger, Cristina Granziera, Maryna Volodimirivna Waszak

This work investigates the possibility of using FID navigator signals to improve the performance of a recently proposed autofocusing-based retrospective motion correction technique. FID navigators were incorporated into an MP-RAGE sequence and 3 subjects w ...

2014

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Jean-Philippe Thiran, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Gloria Menegaz, David Paul Roger Romascano, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Jean-Philippe Thiran, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Gloria Menegaz, David Paul Roger Romascano, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

On the reproducibility and anatomical correspondence of DSI tractography

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Alessandro Daducci, Gunnar Krüger, Leila Cammoun, Cristina Granziera, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

Diffusion spectrum imaging (DSI) is increasingly explored in clinical research. The quantitative value of the DSI technique, however, has still to be established. In this context, a better understanding of the reproducibility and the anatomical corresponde ...

2010

Thrombin-induced ischemic tolerance is prevented by inhibiting c-jun N-terminal kinase

Pierre Magistretti, Cristina Granziera

We have studied ischemic tolerance induced by the serine protease thrombin in two different models of experimental ischemia. In organotypic hippocampal slice cultures, we demonstrate that incubation with low doses of thrombin protects neurons against a sub ...

2007

Structural abnormalities in the thalamus of migraine patients: a multi-parametric study at high field

Alessandro Daducci, Gunnar Krüger, Cristina Granziera, Nouchine Hadjikhani, David Paul Roger Romascano, Alexis Roche

2012