Publications by Andreas Massouras

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The Drosophila melanogaster Genetic Reference Panel (DGRP) is a community resource of 205 sequenced inbred lines, derived to improve our understanding of the effects of naturally occurring genetic variation on molecular and organismal phenotypes. We used a ...

The vast majority of genes in humans and other organisms undergo alternative splicing, yet the biological function of splice variants is still very poorly understood in large part because of the lack of simple tools that can map the expression profiles and ...

Gut immunocompetence involves immune, stress and regenerative processes. To investigate the determinants underlying inter-individual variation in gut immunocompetence, we perform enteric infection of 140 Drosophila lines with the entomopathogenic bacterium ...

Drosophila melanogaster has one of the best characterized metazoan genomes in terms of functionally annotated regulatory elements. To explore how these elements contribute to gene regulation, we need convenient tools to identify the proteins that bind to t ...

High-throughput sequencing (HTS) is revolutionizing our ability to obtain cheap, fast and reliable sequence information. Many experimental approaches are expected to benefit from the incorporation of such sequencing features in their pipeline. Consequently ...

Understanding the relationship between genetic and phenotypic variation is one of the great outstanding challenges in biology. To meet this challenge, comprehensive genomic variation maps of human as well as of model organism populations are required. Here ...

Andreas Massouras

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Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

GETPrime: a gene- or transcript-specific primer database for quantitative real-time PCR

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

Automated protein-DNA interaction screening of Drosophila regulatory elements

WebPrInSeS: automated full-length clone sequence identification and verification using high-throughput sequencing data

Genomic Variation and Its Impact on Gene Expression in Drosophila melanogaster

Discovery and functional characterisation of structural genomic variation in a natural population

Primer-initiated sequence synthesis to detect and assemble structural variants