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Tatjana Petrov

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Related publications (6)

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Lumpability Abstractions of Rule-based Systems

Tatjana Petrov

The induction of a signaling pathway is characterized by transient complex formation and mutual posttranslational modification of proteins. To faithfully capture this combinatorial process in a mathematical model is an important challenge in systems biolog ...

2010

Stochastic fragments: A framework for the exact reduction of the stochastic semantics of rule-based models

Tatjana Petrov

In this paper, we propose an abstract interpretation-based framework for reducing the state space of stochastic semantics for protein protein interaction networks. Our approach consists in quotienting the state space of networks. Yet interestingly, we do n ...

2013

Probability metrics to calibrate stochastic chemical kinetics

Tatjana Petrov

Calibration or model parameter estimation from measured data is an ubiquitous problem in engineering. In systems biology this problem turns out to be particularly challenging due to very short data-records, low signal-to-noise ratio of data acquisition, la ...

2010

Tatjana Petrov

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Lumpability Abstractions of Rule-based Systems

Stochastic fragments: A framework for the exact reduction of the stochastic semantics of rule-based models

Probability metrics to calibrate stochastic chemical kinetics

Combining model reductions

Stochastic Semantics of Signaling as a Composition of Agent-view Automata

Stochastic Semantics of Signaling as a Composition of Agent-view Automata