Nouchine Hadjikhani

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Related publications (32)

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Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

Nouchine Hadjikhani, Fei Chen

Fragile X syndrome (FXS) is an X-linked condition associated with intellectual disability and behavioral problems. It is caused by expansion of a CGG repeat in the 5' untranslated region of the fragile X mental retardation 1 (FMR1) gene. This mutation is a ...

2011

Serotonin, pregnancy and increased autism prevalence: Is there a link?

Nouchine Hadjikhani

The prevalence of autism, a neurodevelopmental condition resulting from genetic and environmental causes, has increased dramatically during the last decade. Among the potential environmental factors, hyperserotonemia during pregnancy and its effect on brai ...

2010

Improving emotional face perception in autism with diuretic bumetanide: A proof-of-concept behavioral and functional brain imaging pilot study

Nouchine Hadjikhani, Loyse Hippolyte, Torsten Ruest

Clinical observations have shown that GABA-acting benzodiazepines exert paradoxical excitatory effects in autism, suggesting elevated intracellular chloride (Cl-)(i) and excitatory action of GABA. In a previous double-blind randomized study, we have shown ...

Sage Publications Ltd2015

Pointing with the eyes: The role of gaze in communicating danger

Nouchine Hadjikhani

Facial expression and direction of gaze are two important sources of social information, and what message each conveys may ultimately depend on how the respective information interacts in the eye of the perceiver. Direct gaze signals an interaction with th ...

Elsevier2008

Diffusion Spectrum Imaging Shows the Structural Basis of Functional Cerebellar Circuits in the Human Cerebellum In Vivo

Reto Meuli, Cristina Granziera, Nouchine Hadjikhani

Background: The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits. Identifying the structural bases of cerebellar neuronal networks in humans in vi ...

2009

Early (M170) activation of face-specific cortex by face-like objects

Nouchine Hadjikhani

The tendency to perceive faces in random patterns exhibiting configural properties of faces is an example of pareidolia. Perception of 'real' faces has been associated with a cortical response signal arising at approximately 170 ms after stimulus onset, bu ...

Lippincott, Williams & Wilkins2009

Investigating Gaze of Children with ASD in Naturalistic Settings

Aude Billard, Nouchine Hadjikhani, Basilio Noris

Background: Visual behavior is known to be atypical in Autism Spectrum Disorders (ASD). Monitor-based eye-tracking studies have measured several of these atypicalities in individuals with Autism. While atypical behaviors are known to be accentuated during ...

Public Library of Science2012

Structural abnormalities in the thalamus of migraine patients: a multi-parametric study at high field

Alessandro Daducci, Gunnar Krüger, Cristina Granziera, Nouchine Hadjikhani, David Paul Roger Romascano, Alexis Roche

2012

Stimulus duration can change polarity of BOLD response in the amygdalae: a 7T fMRI study

Wietske Van der Zwaag, Nouchine Hadjikhani, Sandra Elisabete Monney

2011

Developmental Prosopagnosia In A Patient With Hypoplasia Of The Vermis Cerebelli

Nouchine Hadjikhani, Qing Zhu

2012

A new early and automated MRI-based predictor of motor improvement after stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Gunnar Krüger, Djalel Eddine Meskaldji, Cristina Granziera, Nouchine Hadjikhani, Alexis Roche, Richard Frackowiak

Objectives: In this study, we investigated the structural plasticity of the contralesional motor network in ischemic stroke patients using diffusion magnetic resonance imaging (MRI) and explored a model that combines a MRI-based metric of contralesional ne ...

2012

A 7 tesla FMRI study of amygdala responses to fearful faces

Wietske Van der Zwaag, Nouchine Hadjikhani, Sandra Elisabete Monney

The amygdalae are involved in the perception of emotions such as happiness, anger and fear. Because of their proximity to the sinuses, the image signal intensity in T2* weighted fMRI data is often affected by signal loss due to through-slice dephasing, esp ...

2012