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Lijing Xin

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Related publications (123)

BISEP-based, Ultra-short TE 1H–[13C] NMR Spectroscopy of the Rat Brain at 14.1 T

Bernard Lanz, Rolf Gruetter, Lijing Xin, Hanne Frenkel

2009

Comparison of glutamate and glutamine quantitation in rat brain by 1H-[13C] NMR Spectroscopy at 9.4 T and 14.1 T

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2009

In vivo measurement of glycine with short echo-time H-1 MRS in human brain at 7 T

Rolf Gruetter, Giulio Gambarota, Lijing Xin, Wietske Van der Zwaag, Gunnar Krüger

To determine whether glycine can be measured at 7 T in human brain with H-1 magnetic resonance spectroscopy (MRS). ...

2009

Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Knowledge of T-1 relaxation times can be important for accurate relative and absolute quantification of brain metabolites, for sensitivity optimizations, for characterizing molecular dynamics, and for studying changes induced by various pathological condit ...

Wiley-Blackwell2009

NMR determination of brain glycogen turnover with internal labelling monitoring

Rolf Gruetter, Ruud van Heeswijk, Lijing Xin

Wiley-Blackwell2009

Selective Resonance Suppression H-1-[C-13] NMR Spectroscopy With Asymmetric Adiabatic RF Pulses

Rolf Gruetter, Lijing Xin, Hanne Frenkel

Despite obvious improvements in spectral resolution at high magnetic field, the detection of C-13 labeling by H-1-[C-13] NMR spectroscopy remains hampered by spectral overlap, such as in the spectral region of H-1 resonances bound to C3 of glutamate (Glu) ...

Wiley-Blackwell2009

Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Reliable quantification of the macromolecule signals in short echo-time H-1 MRS spectra is particularly important at high magnetic fields for an accurate quantification of metabolite concentrations (the neurochemical profile) due to effectively increased s ...

2009

Glycine Tissue Level in Medulla Oblongata Measured in vivo with 1H MRS at 9.4 T in Rat Brain

Rolf Gruetter, Giulio Gambarota, Lijing Xin, João Miguel das Neves Duarte

2009

Time-resolved measurement of rat brain glycogen absolute concentration in vivo

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

Wiley-Blackwell2009

Improved Spectral Dispersion in Proton MR Spectroscopy of the Neurochemical Profile in the Rat Brain at 14.1 Tesla

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

1H NMR T1 Relaxation Times of the Neurochemical Profiles in Rat Brain at 14.1T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

In vivo H-1 NMR measurement of glycine in rat brain at 9.4 T at short echo time

Chiara Perazzolo, Rolf Gruetter, Giulio Gambarota, Lijing Xin

Glycine is an amino acid present in mammalian brain, where it acts as an inhibitory and excitatory neurotransmitter. The two detectable protons of glycine give rise to a singlet at 3.55 ppm that overlaps with the more intense myo-inositol resonances, and i ...

Wiley-Blackwell2008

Proton T-2 relaxation time of J-coupled cerebral metabolites in rat brain at 9.4T

Rolf Gruetter, Giulio Gambarota, Lijing Xin

Knowledge of proton T-2 relaxation time of metabolites is essential for proper quantitation of metabolite concentrations in localized proton spectroscopy, especially at moderate to long TEs. Although the T-2 relaxation time of singlets, such as that of cre ...

Wiley-Blackwell2008

Comparison of Two Approaches to Model the Macromolecule Spectrum for the Quantification of Short TE 1H MRS Spectra at 14.1T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

Localized 1H[13C] NMR Measurement of N-acetyl-aspartate Turnover in Rat Brain

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2008

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Accurate assessment of the macromolecule contributions in short echo-time proton MRS spectra is important for a reliable quantification of the neurochemical profile. The aim of the present study was to assess two approaches based on using LCModel, which ta ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2008

Comparison of the T1 of the neurochemical profile in rat brain at 9.4T and 14.1T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

Non-invasive quantification of brain glycogen absolute concentration

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Ultra-short echo-time proton single voxel spectra of rat brain were obtained on a 14.1 T 26 cm horizontal bore system. At this field, the fitted linewidth in the brain tissue of adult rats was about 11 Hz. New, separated resonances ascribed to phosphocholi ...

Academic Press Inc - Elsevier Science2008

Hahn T2 Relaxation Times of the Neurochemical Profile at 14.1T in the in vivo Rat Brain

Rolf Gruetter, Giulio Gambarota, Lijing Xin, Cristina Ramona Cudalbu

2008

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