Laurent Renaud Uldry

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Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...

Purpose: Distinguishing persistent from permanent atrial fibrillation (AF) in a reliable way would improve AF patient management, as cardioversion options could be considered appropriately. In this study, complexity measures based on the combined analysis ...

This study presents an automatic diagnostic method for the discrimination between persistent and long-standing atrial fibrillation (AF) based on the surface electrocardiogram (ECG). Standard 12-lead ECG recordings were acquired in 53 patients with either p ...

Purpose: Non-invasively predicting the success of pharmacological cardioversion for patients with atrial fibrillation (AF) would be of great interest in clinical settings. In this study, an adaptive algorithm for tracking fundamental and harmonic component ...

BACKGROUND Termination of persistent atrial fibrillation (AF) is a valuable ablation endpoint but is difficult to anticipate. We evaluated whether temporal and spatial indices of AF regularization predict intraprocedural AF termination and outcome. ...

While successful termination by pacing of organized atrial tachycardias has been observed in patients, rapid pacing of AF can induce a local capture of the atrial tissue but in general no termination. The purpose of this study was to perform a systematic e ...

Aims To present a comparison of electrocardiogram-based non-invasive measures of atrial fibrillation (AF) substrate complexity computed on invasive animal recordings to discriminate between short-term and long-term AF. The final objective is the selection ...

We studied the mechanisms of spontaneous termination of atrial fibrillation in a biophysical model of human atria, during the eight seconds preceding termination. The earliest detectable changes in the cycle length and the number of wavefronts occurred abo ...

The standard ECG remains the most common non-invasive tool for assessing atrial fibrillation. Specific signal processing techniques have been developed to improve the diagnosis. However, validation of such tools is challenging and comprehensive invasive da ...

Due to their transient nature, spontaneous terminations of atrial fibrillation (AF) are difficult to investigate. Apparently, confounding experimental findings about the time scale of this phenomenon have been reported, with values ranging from 1 s to 1 mi ...

Neuronal oscillations are an important aspect of EEG recordings. These oscillations are supposed to be involved in several cognitive mechanisms. For instance, oscillatory activity is considered a key component for the top-down control of perception. Howeve ...

Purpose: Experimental studies showed that local capture of atrial fibrillation (AF) by rapid pacing was possible in humans. However, contradictory observations were reported on its effect at distant atrial sites. The present model-based study investigated ...

Aims While successful termination by pacing of organized atrial tachycardias has been observed in patients, single site rapid pacing has not yet led to conclusive results for the termination of atrial fibrillation (AF). The purpose of this study was to eva ...

We present a model-based systematic study of antitachycardia pacing protocols applied to atrial fibrillation, focusing on the ability to achieve and maintain capture during pacing, as a function of both pacing site and period. We observed that pacing sites ...

Laurent Renaud Uldry

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Therapeutic Strategies for the Treatment of Atrial Fibrillation : New Insights from Biophysical Modeling and Signal Processing

Novel complexity measurements in the ECG differentiate persistent from permanent atrial fibrillation

Measures of spatiotemporal organization differentiate persistent from long-standing atrial fibrillation

Harmonic frequency tracking algorithm for predicting the success of pharmacological cardioversion of atrial fibrillation

Early temporal and spatial regularization of persistent atrial fibrillation predicts termination and arrhythmia-free outcome

Optimizing Local Capture of Atrial Fibrillation by Rapid Pacing: Study of the Influence of Tissue Dynamics

Systematic comparison of non-invasive measures for the assessment of atrial fibrillation complexity: a step forward towards standardization of atrial fibrillation electrogram analysis

Spontaneous termination of atrial fibrillation: study of the effect of atrial geometry in a biophysical model

The Role of Atrial Modeling in the Development of ECG Processing Tools

Estimating the time scale and anatomical location of atrial fibrillation spontaneous termination in a biophysical model

Adaptive tracking of EEG oscillations

Study of the effect of rapid pacing of atrial fibrillation on the non-paced atrium

Atrial septal pacing for the termination of atrial fibrillation: study in a biophysical model of human atria

Estimation of tissue wavelength predicts the feasibility of local capture by rapid pacing in atrial fibrillation

Optimization of antitachycardia pacing protocols applied to atrial fibrillation: insights from a biophysical model

Temporal and spatial regularization of persistent atrial fibrillation is associated with arrhythmia free outcome

The effect of pacing site and frequency on capture of atrial fibrillation observed in a biophysical model

Influence of pacing site on the spatial extent of capture during atrial fibrillation rapid pacing

Early temporal and spatial regularization during ablation of persistent atrial fibrillation predicts arrhythmia termination

Effect of atrial fibrillation dynamics on the mechanisms of spontaneous termination