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Paulina Izewska

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Related publications (4)

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Investigating the molecular basis of ligand binding to and activation of olfactory receptors in living cells

Paulina Izewska

The olfactory system is a highly specialized chemodetector capable of discriminating between thousands of volatile chemical substances. This enormous capacity of chemical recognition is based on a large family of olfactory receptors (ORs). Despite the fact ...

EPFL2006

Diffusion-Time Distribution Analysis Reveals Characteristic Ligand-Dependent Interaction Patterns of Nuclear Receptors in Living Cells

Horst Arthur Vogel, Horst Pick, Hanna Jankevics, Paulina Izewska

Nuclear receptors initiate transcription, interact with regulatory proteins, and are influenced by hormones, drugs, and pollutants. Herein, we discover ligand-specific mobility patterns of human estrogen receptor-a (ER) in living cells using diffusion-time ...

2005

Pumping of mammalian cells with a nozzle-diffuser micropump

Martinus Adela Maria Gijs, Horst Arthur Vogel, Caroline Vandevyver, Christophe Yamahata, Frédéric Lacharme, Paulina Izewska

We discuss the successful transport of jurkat cells and 5D10 hybridoma cells using a reciprocating micropump with nozzle-diffuser elements. The effect of the pumping action on cell viability and proliferation, as well as on the damaging of cellular membran ...

Royal Society of Chemistry2005

Multifunctional Lipid/Quantum-Dots Hybrid Nanocontainers for Controlled Targeting of Live Cells

Horst Arthur Vogel, Davide Demurtas, Christophe Danelon, Pierre-Yves Bolinger, Gopakumar Gopalakrishnan, Paulina Izewska, Isabelle Geissbühler Bärlocher

In this communication, we report on an interesting observation of wide-ranging potential for cellular imaging and manipulation: Hydrophobic QDs can be easily incorporated into the bilayer membrane of lipid vesicles. Such lipid/QD nanocontainer hybrid vesic ...

Wiley-VCH Verlag GmbH2006