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Reto Meuli

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Related publications (80)

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Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Gloria Menegaz

Objectives: Contralesional brain connectivity plasticity was previously reported after stroke. This study aims at disentangling the biological mechanisms underlying connectivity plasticity in the uninjured motor network after an ischemic lesion. In particu ...

2015

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Pierre Magistretti, Reto Meuli

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h i ...

Mary Ann Liebert2016

A Multi-Contrast MRI Study of Microstructural Brain Damage in Patients with Mild Cognitive Impairment

Meritxell Bach Cuadra, Reto Meuli, Alessandro Daducci, Cristina Granziera, Daniel Andreas Schmitter, Alexis Roche, Guillaume Bonnier

Objectives: The aim of this study was to investigate pathological mechanisms underlying brain tissue alterations in mild cognitive impairment (MCI) using multi-contrast 3 T magnetic resonance imaging (MRI). Methods: Forty-two MCI patients and 77 healthy co ...

Elsevier2015

A statistical shape model of the human second cervical vertebra

Reto Meuli, Simon Nessim Henein, Charles Baur, Marine Chantal Elisabeth Geneviève Clogenson

Statistical shape and appearance models play an important role in reducing the segmentation processing time of a vertebra and in improving results for 3D model development. Here, we describe the different steps in generating a statistical shape model (SSM) ...

Springer Heidelberg2015

White matter maturation reshapes structural connectivity in the late developing human brain

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Leila Cammoun, Leila Faiza Ben Hamida Cammoun

From toddler to late teenager, the macroscopic pattern of axonal projections in the human brain remains largely unchanged while undergoing dramatic functional modifications that lead to network refinement. These functional modifications are mediated by inc ...

National Academy of Sciences2010

Automatic quality assessment in structural brain magnetic resonance imaging

Jean-Philippe Thiran, Reto Meuli, Gunnar Krüger, Bénédicte Marie Maréchal

MRI has evolved into an important diagnostic technique in medical imaging. However, reliability of the derived diagnosis can be degraded by artifacts, which challenge both radiologists and automatic computer-aided diagnosis. This work proposes a fully-auto ...

Wiley2009

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

Reto Meuli, Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Jonas Richiardi, Francesco La Rosa, João Pedro Forjaco Jorge

The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine is limited by inter-rater variability and the expenditure of time associated with manual assessment. We describe a ...

2020

Topography of EEG multivariate phase synchronization in early Alzheimer's disease

Reto Meuli, Martin Hasler, Mahdi Jalili

Alzheimer's disease (AD) is likely to disrupt the synchronization of the bioelectrical processes in the distributed cortical networks underlying cognition. We analyze the surface topography of the multivariate phase synchronization (MPS) of multichannel EE ...

2010

Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Leila Cammoun, Djalel Eddine Meskaldji, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

There is growing interest in understanding the role of the non-injured contra-lateral hemisphere in stroke recovery. In the experimental field, histological evidence has been reported that structural changes occur in the contra-lateral connectivity and cir ...

2011

Understanding Diffusion MR Imaging Techniques: From Scalar Diffusion-weighted Imaging to Diffusion Tensor Imaging and Beyond

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Lisa Jonasson

The complex structural organization of the white matter of the brain can be depicted in vivo in great detail with advanced diffusion magnetic resonance (MR) imaging schemes. Diffusion MR imaging techniques are increasingly varied, from the simplest and mos ...

2006

Mapping the Structural Core of Human Cerebral Cortex

Reto Meuli, Patric Hagmann, Leila Cammoun, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun, Pascal Hagmann

Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. Using diffusion spectrum imaging we noninvasively map these pathways within and across cort ...

2008

An X-ray computed tomography-based index to characterize the quality of cataclastic carbonate rock samples

Aurèle Parriaux, Reto Meuli, Vincent Labiouse, Pascal Turberg

X-ray computed tomography (XRCT) can reconstruct, in a nondestructive way and in three-dimension, the distribution of densities within opaque materials. Consequently, it provides an effective possibility to characterize the inner content of rock core sampl ...

2011

Validating atlas-based lesion disconnectomics in multiple sclerosis: A retrospective multi-centric study

Reto Meuli, Tobias Kober, Bénédicte Marie Maréchal, Jonas Richiardi

The translational potential of MR-based connectivity modelling is limited by the need for advanced diffusion imaging, which is not part of clinical protocols for many diseases. In addition, where diffusion data is available, brain connectivity analyses rel ...

2021

How much confidence do we have in a MRI tractography experiment?

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Xavier Gigandet

When performing a tractography experiment it is essential to know whether a reconstructed tract results from the diffusion signal itself or from some random effect or noise. In this study, we introduce a way to associate to every connection a confidence le ...

IEEE2007

The Connectome Viewer Toolkit: an open source framework to manage, analyze, and visualize connectomes

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Alessandro Daducci, Alia Lemkaddem

Advanced neuroinformatics tools are required for methods of connectome mapping, analysis, and visualization. The inherent multi-modality of connectome datasets poses new challenges for data organization, integration, and sharing. We have designed and imple ...

Frontiers Research Foundation2011

In-vivo magnetic resonance imaging of the structural core of the Papez circuit in humans

Reto Meuli, Cristina Granziera, Nouchine Hadjikhani

Papez circuit is one of the major pathways of the limbic system, and it is involved in the control of memory and emotion. Structural and functional alterations have been reported in psychiatric, neurodegenerative, and epileptic diseases. Despite the clinic ...

2011

Automatic quality assessment in structural brain magnetic resonance imaging

Jean-Philippe Thiran, Reto Meuli, Gunnar Krüger, Bénédicte Marie Maréchal

Quality assessment of MRI is of great importance to derive reliable diagnostic information. As automated quantitative image analysis is being increasingly used in routine, automated measures of quality are needed. Based on a single magnitude image, we prop ...

2009

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Meritxell Bach Cuadra, Alessandro Daducci, Reto Meuli, Gunnar Krüger, Bénédicte Marie Maréchal, Cristina Granziera, Alexis Roche, Delphine Ribes Lemay, Daniel Andreas Schmitter

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Proceedings of 23rd International Society for Magnetic Resonance in Medicine (ISMRM) Conference2014

Diffusion MR Image Segmentation: Towards Global Brain Connectivity Analysis

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Leila Cammoun, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

The exploration of the human connectome, a term denoting the global structural connectivity of the brain, is accessible to MRI at millimeter and centimeter scales. In this paper, we propose a methodology to map the connectome by constructing normalized who ...

Societa Editrice Esculapio-Progetto Leonardo, Via Umberto Terracini 30, Bologna, 40131, Italy2009

Evolution of source EEG synchronization in early Alzheimer's disease

Reto Meuli, Cristian Carmeli, Alireza Khadivi

Alzheimer's disease (AD) disrupts functional connectivity in distributed cortical networks. We analyzed changes in the S-estimator, a measure of multivariate intraregional synchronization, in electroencephalogram (EEG) source space in 15 mild AD patients v ...

Elsevier2013