Publications by Ian William Marison

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

For many years, calorimetry has been recognized as a powerful and universal tool for monitoring chem. and biol. processes. A lab.-scale reaction calorimeter (RC1, Mettler-Toledo), initially developed for chem. reaction studies with a sensitivity of 100-150 mW/l, has been improved to enable the monitoring of very low heat prodn. rates (

An on-line pH monitoring method based on mid-infrared spectroscopy relevant to bioprocesses is presented. This approach is non-invasive and does not require the addition of indicators or dyes, since it relies on the analysis of species of common buffers us ...

In recent years ever-increasing amounts of pharmaceuticals are being detected in the aquatic environment and in some cases, they have even been discovered in drinking water. Their presence is attributed mainly to the inability of sewage treatment plants to ...

A new approach combining electrostatic and covalent bonds was established for the formation of resistant capsules with long-term stability under physiol. conditions. Three kinds of interactions were generated in the same membrane: (1) electrostatic bonds b ...

Spores of Bacillus subtilis ATCC 6051 and Bacillus stearothermophilus NCTC 10003 were immobilized in monodisperse alginate beads (diameter, 550 microm +/- 5%), and the capacity of the immobilized bioindicators to provide accurate and reliable F-values for sterilization processes was studied. The resistance of the beads to abrasion and heat was strong enough to ensure total retention of the bioindicators in the beads in a sterilization cycle. D- and z-values for free spores were identical to those for immobi

An encapsulation device, designed on the basis of the laminar jet break-up technique, is characterized for cell immobilization with different types of alginate. The principle of operation of the completely sterilizable encapsulator, together with techniques for the continuous prodn. of beads from 250 mm to 1 mm in diam., with a size distribution below 5%, at a flow rate of 1-15 mL/min, is described. A modification of the device, to incorporate an electrostatic potential between the alginate droplets and an

A binned Dalitz plot analysis of B-+/- -> DK +/- decays, with D -> K-S(0)pi(+)pi(-) and D -> (KSK+K-)-K-0, is used to perform a measurement of the CP-violating observables x(+/-) and y(+/-), which are sensitive to the Cabibbo-Kobayashi-Maskawa angle gamma. ...

A review with many refs. Ammonia has been reported to be toxic and inhibitory for mammalian cell cultures for many years. Redn. of growth rates and maximal cell densities in batch cultures, changes in metabolic rates, perturbation of protein processing and virus replication have been reported. However, cellular mechanisms of ammonia toxicity are still the subject of controversy and are presented here. The phys. and chem. characteristics of ammonia and ammonium are important, with the former capable of readi

Calorimetry has shown real potential at bench-scale for chem. and biochem. processes. The aim of this work was therefore to scale-up the system by adaptation of a std. com. available 300-L pilot-scale bioreactor. To achieve this, all heat flows entering or leaving the bioreactor were identified and the necessary instrumentation implemented to enable online monitoring and dynamic heat balance estn. Providing that the signals are sufficiently precise, such a heat balance would enable calcn. of the heat releas

This paper attempts to review in how far thermodn. anal. can be used to understand and predict the performance of microorganisms with respect to growth and bioproduct synthesis. In the first part, a simple thermodn. model of microbial growth is developed w ...

The production of (nS) mesons (n = 1; 2; 3) in p Pb and Pb p collisions at a centre-of-mass energy per nucleon pair p sNN = 8 : 16TeV is measured by the LHCb experiment, using a data sample corresponding to an integrated luminosity of 31.8 nb. The (nS) mes ...

A perstraction system using liq.-core microcapsules for pesticide and herbicide removal from aq. environments is proposed. The microcapsules contain an oil, di-Bu sebacate, surrounded by a hydrogel membrane. The extn. efficiency of the capsules was demonstrated with atrazine, methylparathion, ethylparathion, and 2,4-dichloro-phenoxyacetic acid. The results show that all of the tested compds. could be rapidly extd., typically 75% extn. within 10 min using a capsule: liq. vol. ratio of only 3.5% for ethylpara

This article presents the first measurement of the differential Z-boson production cross-section in the forward region using proton-lead collisions with the LHCb detector. The dataset was collected at a nucleon-nucleon centre-of-mass energy of root(NN)-N-s ...

A measurement of Z -> tau(+)tau(-) production cross-section is presented using data, corresponding to an integrated luminosity of 2 fb(-1), from pp collisions at root s = 8 TeV collected by the LHCb experiment. The tau(+)tau(-)candidates are reconstructed ...

The calorimetric response of the yeast Kluyveromyes fragilis was investigated for growth in continuous culture where N limitation was imposed on a C-limited culture. Calorimetric measurements were combined with off gas anal., measurements of biomass, substrate and product concns., elemental biomass compn., and heat prodn. to study the physiol. response of K. fragilis. Regions where both carbon and nitrogen limited growth, were found over a broad range of diln. rates and feed carbon-to-nitrogen ratios. The p

A recombinant avidin-producing Mut(+) Pichia pastoris strain was used as a model organism to study the influence of the methanol feeding strategy on the specific product productivity (q(p)) and protein glycosylation. Fed-batch cultivations performed at var ...

Bubble-free aeration is applied in animal cell culture processes for oxygenation to avoid shear stress and foaming assocd. with direct sparging into the culture. Oxygen mass transfer across PTFE-membranes was detd. in three different reactor systems that may be applied to animal cell cultures. Oxygen was supplied on the aeration side of the membrane by air- or oxygen-satd. aq. liqs., or directly using air or pure oxygen. By using liqs., the bubble-free aeration may be combined with an ammonia removal system

A system for the independent control of ammonia and glutamine in a hollow-fiber reactor has been developed. Online anal. of the two chem. species was performed using FIA. A custom-made program has been written to fully automate the FIA, to perform measurements, calibrations and data acquisition, and to activate two peristaltic feed pumps. Diagnostic tests were also automatically performed in order to identify, and in some cases eliminate, erroneous measurements and calibrations due to instrument failures. F

Due to residual oil retained within it, rapeseed press-cake has been shown to be effective for the removal of atrazine from water through an absorption mechanism. However, it is difficult to put this into practice due to the hygroscopic nature of the press ...

An amplitude analysis of the D+-> (-)pi(+)pi(+) decay is performed with a sample corresponding to 1.5 fb(-1) of integrated luminosity of pp collisions at a centre-of-mass energy root s = 8 TeV collected by the LHCb detector in 2012. The sample contains app ...

Ian William Marison

Chat with Graph Search

Quantitative calorimetric investigation of fed-batch cultures of Bacillus sphaericus 1593M

pH prediction and control in bioprocesses using mid-infrared spectroscopy

Removal of pharmaceuticals from water: Using liquid-core microcapsules as a novel approach

Formation of Microcapsules from Polyelectrolyte and Covalent Interactions

Immobilized bacterial spores for use as bioindicators in the validation of thermal sterilization processes

Characterization of an encapsulation device for the production of monodisperse alginate beads for cell immobilization

Measurement of the CKM angle gamma using B-+/- -> DK +/- with D -> K-S(0)pi(+)pi(-), (KSK+K-)-K-0 decays

The importance of ammonia in mammalian cell culture

Development of a large-scale biocalorimeter to monitor and control bioprocesses

Thermodynamics of microbial growth and metabolism: An analysis of the current situation

Study of Gamma production in pPb collisions at root(s)(NN) (=)8.16 TeV

A novel approach for the extraction of herbicides and pesticides from water using liquid-core microcapsules

Measurement of the Z boson production cross-section in proton-lead collisions at root(NN)-N-s=8.16 TeV

Measurement of Z -> tau(+)tau(-) production in proton-proton collisions at root s=8 TeV

Calorimetric and stoichiometric analysis of growth of Kluyveromyces fragilis in continuous culture. Nitrogen limitation imposed upon carbon-limited growth

Influence of specific growth rate on specific productivity and glycosylation of a recombinant avidin produced by a Pichia pastoris Mut(+) strain

Bubble-free oxygenation by means of hydrophobic porous membranes

Development of an online control system for the cultivation of animal cells in a hollow-fiber reactor using flow injection analysis and a visual programming language

Immobilization of rapeseed press-cake in an alginate matrix for the sorption of atrazine

Amplitude analysis of the D+-> pi(-)pi(+)pi(+) decay and measurement of the pi(-)pi(+) S-wave amplitude