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Neuroscience Reconstructed: Genetics and Brain Development

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Lectures in this MOOC (73)

Production of Viral Vectors MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores the production of viral vectors for gene therapy applications, emphasizing AAV vectors and the process of large-scale production and purification.

Gene Regulatory Networks MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores how gene regulatory networks encode changes in cell development and the importance of interactions between different regulatory networks.

Modeling: Principles and Applications MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores the basics of modeling in systems neuroscience and the importance of experimental data analysis.

Clinical Trials: Phases and Challenges MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Covers clinical trial phases, challenges in rare diseases, and placebo control.

Genome Sequencing and Autism Neurobiology MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Covers the process of library preparation and data processing in genome sequencing, and discusses a large-scale study on autism neurobiology.

Neurulation: Neural Crest Cells MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores neurulation and the crucial role of neural crest cells in nervous system development.

Gene Regulation: Transcription Mechanisms and Chromatin Accessibility MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores gene regulation through transcription mechanisms and chromatin accessibility, emphasizing the importance of transcription factors and gene regulatory networks.

Regionalization: Early Brain Development MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores the early regionalization of the brain and the differentiation and migration of cells in specific brain regions.

Rules of Development MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Delves into cell-autonomous processes, extrinsic regulation, and cell interactions in development.

Developmental Timeline: Brain Neurogenesis and Growth MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores the brain's developmental timeline from neurulation to adult growth.

Building blocks of a gene: Regulation of transcription MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores the regulation of transcription and its impact on gene expression.

Gene interactions and networks MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores gene interactions, regulatory networks, genetic variability, and computational models for genetic dynamics.

The Whole Brain Abstraction and Infrastructure MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Covers the modeling of electrophysiology at different scales and the infrastructure for brain simulation and analysis.

Sequencing: Sanger and Illumina MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores Sanger sequencing principles, limitations, and newer Illumina sequencing methods for high-throughput DNA analysis.

Spinal Muscular Atrophy: Genetic Insights and Therapeutic Strategies MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores Spinal Muscular Atrophy, discussing disease classes, genetic mechanisms, and gene therapy strategies for potential clinical benefits.

Untitled MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Approaches in Gene Therapy MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Discusses approaches in gene therapy for different diseases and the advantages of gene transfer over conventional drugs, as well as viral vectors for gene delivery.

Genomics Tools in Neuroscience Research MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores gene regulation, genomics tools, DNA sequencing, and PCR in neuroscience research.

Choosing a Viral Vector and Delivery Method MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Discusses viral vector selection for gene therapy, with a focus on AAV vectors for SMA1 therapy and CNS delivery.

Gene Transcription MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Covers the process of gene transcription, RNA processing, nuclear export, and translation.

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