Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.
Explores deciphering protein interaction fingerprints using geometric deep learning and the challenges in computational protein-protein interaction design.
Delves into protein folding principles, emphasizing sequence's role in determining structure and exploring thermodynamics and intermolecular interactions.
Explores the conformational and functional flexibility of Hsp70 molecular chaperones, focusing on folding intermediates and the Hsp70 functional cycle.
Covers challenges in protein design, energy functions, search algorithms, and applications in synthetic biology, emphasizing the importance of protein design and the methods used for designing proteins.