Lectures related to Nuclear Receptors: Core Signaling

Drug Targets: Nuclear Receptors

Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.

Nuclear Receptors: Drug Targets

Explores nuclear receptors, their role in drug pharmacology, and physiological functions in adipose tissue and glucose homeostasis.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Cell Signalling: Receptors and Pathways

Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.

Cellular Communication: Signaling Pathways and Receptors

Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.

Regulation Mechanisms Overview

Covers phosphorylation, ubiquitinylation, methylation, and more in biological regulation.

Prokaryotic Transcription: Operons and Sigma Factors

Explores prokaryotic transcription, operons, sigma factors, gene regulation, and DNA loops in bacteria.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

Heat Shock Transcription Factors: Regulation and Targets

Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.

Gene Regulatory Networks MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores how gene regulatory networks encode changes in cell development and the importance of interactions between different regulatory networks.

Cell Signaling and Genetic Inheritance

Explores cell signaling mechanisms and genetic inheritance related to hair pigmentation.

Eukaryotic Transcription: Initiation and Elongation

Explores eukaryotic transcription initiation, elongation, and gene regulation complexity.

Melanocytes and Hair Color Regulation

Examines paracrine communication in melanocytes, CAMP influence on hair color, Mc4R mutations, and fur phenotypes.

Gene Regulation: Transcription Mechanisms and Chromatin Accessibility MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores gene regulation through transcription mechanisms and chromatin accessibility, emphasizing the importance of transcription factors and gene regulatory networks.

Synthetic biology: molecular components and cellular engineering

Delves into synthetic biology, assembling molecular components for biological functions in living cells, including gene expression control and engineered receptor signaling.

Nuclear Receptors: Signalling and Health Implications Log in to Mediaspace to watch this video

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

Receptor Tyrosine Kinases: Signalling and Regulation Log in to Mediaspace to watch this video

Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.

G Protein-Coupled Receptors: Signalling Diversity Log in to Mediaspace to watch this video

Explores G protein-coupled receptors' signalling diversity, covering structure, activation, bias effects, and internalisation.

Nuclear Receptors: Coactivators and Transcriptional Modulation Log in to Mediaspace to watch this video

Explores coactivators' role in transcriptional modulation, histone acetylation, ERa antagonists, and tissue-specific actions of nuclear receptors.

Rules of Development Log in to Mediaspace to watch this video

Delves into the rules of development, emphasizing the role of signals and morphogens.