Lecture

Electrical Stimulation: Mechanisms and Applications

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In course

MICRO-560: BioMEMS

This course covers the main applications of micro devices for life science and biomedical applications. The course is organized by application topic. It is also covering the basic physical, biological, chemical, technological concepts, which are presented ...

Description

This lecture covers the principles of electrical stimulation of tissues, including the equivalent circuit model, neuron stimulation mechanisms, charge injection mechanisms, and the effects of electrode capacitance. It explains the importance of biphasic pulses, conductive polymer coatings, and charge-balanced waveforms to prevent tissue damage. The lecture also discusses the limitations of different materials for charge injection, such as platinum and iridium oxide, and the impact of electrode damage on stimulation efficiency.

Instructor

Philippe Renaud

Philippe Renaud is Professor at the Microsystem Laboratory (LMIS4) at EPFL. He is also the scientific director of the EPFL Center of MicroNanoTechnology (CMI). His main research area is related to micronano technologies in biomedical applications (BioMEMS) with emphasis on cell-chips, nanofluidics and bioelectronics. Ph. Renaud is invloved in many scientifics papers in his research area. He received his diploma in physics from the University of Neuchâtel (1983) and his Ph.D. degree from the University of Lausanne (1988). He was postdoctoral fellow at University of California, Berkeley (1988-89) and then at the IBM Zürich Research Laboratory in Switzerland (1990-91). In 1992, he joined the Sensors and Actuators group of the Swiss Center for Electronics and Microtechnology (CSEM) at Neuchâtel, Switzerland. He was appointed assistant professor at EPFL in 1994 and full professor in 1997. In summer 1996, he was visiting professor at the Tohoku University, Japan. Ph. Renaud is active in several scientific committee (scientific journals, international conferences, scientific advisory boards of companies, PhD thesis committee). He is also co-founder of the Nanotech-Montreux conference. Ph. Renaud is committed to valorization of basic research through his involvement in several high-tech start-up companies.

Official source

Related concepts (29)

Equivalent circuit

In electrical engineering, an equivalent circuit refers to a theoretical circuit that retains all of the electrical characteristics of a given circuit. Often, an equivalent circuit is sought that simplifies calculation, and more broadly, that is a simplest form of a more complex circuit in order to aid analysis. In its most common form, an equivalent circuit is made up of linear, passive elements. However, more complex equivalent circuits are used that approximate the nonlinear behavior of the original circuit as well.

Lumped-element model

The lumped-element model (also called lumped-parameter model, or lumped-component model) is a simplified representation of a physical system or circuit that assumes all components are concentrated at a single point and their behavior can be described by idealized mathematical models. The lumped-element model simplifies the system or circuit behavior description into a topology. It is useful in electrical systems (including electronics), mechanical multibody systems, heat transfer, acoustics, etc.

Magnetic circuit

A magnetic circuit is made up of one or more closed loop paths containing a magnetic flux. The flux is usually generated by permanent magnets or electromagnets and confined to the path by magnetic cores consisting of ferromagnetic materials like iron, although there may be air gaps or other materials in the path. Magnetic circuits are employed to efficiently channel magnetic fields in many devices such as electric motors, generators, transformers, relays, lifting electromagnets, SQUIDs, galvanometers, and magnetic recording heads.

LC circuit

File:LC parallel simple.svg|LC circuit diagram File:Low cost DCF77 receiver.jpg|LC circuit ''(left)'' consisting of ferrite coil and capacitor used as a tuned circuit in the receiver for a [[radio clock]] File:Tuned circuit of shortwave radio transmitter from 1938.jpg|Output tuned circuit of [[shortwave]] [[radio transmitter]] An LC circuit, also called a resonant circuit, tank circuit, or tuned circuit, is an electric circuit consisting of an inductor, represented by the letter L, and a capacitor, represented by the letter C, connected together.

Network analysis (electrical circuits)

In electrical engineering and electronics, a network is a collection of interconnected components. Network analysis is the process of finding the voltages across, and the currents through, all network components. There are many techniques for calculating these values; however, for the most part, the techniques assume linear components. Except where stated, the methods described in this article are applicable only to linear network analysis.

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