Lectures related to Synthetic Biology Standardization

Targeting Glycolysis and Cancer Signaling

Explores targeting glycolysis and cancer signaling switches, enzyme inhibition mechanisms, and the role of ATP as the body's energy currency.

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, tumor suppressor genes, metastasis, and genetic alterations driving tumorigenesis.

Metabolic Pathways Tracking: Isotope Tracing Profiling

Explores tracking metabolic pathways through isotope tracing for quantitative metabolomics profiling.

Cellular Communication and Metabolism: Energy Transformation Principles

Discusses cellular communication, metabolism, energy transformation, and the role of enzymes in biochemical reactions.

Altered Metabolism in Cancer: Warburg Effect and MYC Regulation

Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.

Sustained Proliferation: RTK/PI3K/mTOR Pathway in Cancer

Explores the RTK/PI3K/mTOR pathway in cancer, inhibitors, completed trials, and effects of Akt/PKB on survival and proliferation.

What is cancer? - De Palma

Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.

Sustained Proliferation: Signaling Pathways and Cancer Genes

Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.

Nexus Fusion: Collaborative Data Discovery MOOC: Simulation Neurocience

Covers Nexus Fusion, a platform for collaborative data and knowledge discovery, including data management, presentation, and searching.

Synthetic Biology Standardization Log in to Mediaspace to watch this video

Emphasizes standardization in Synthetic Biology, logic rules, chassis cells, and metabolic engineering transition.

Metabolic Engineering: Systems Biology and Tools Log in to Mediaspace to watch this video

Explores systems biology of metabolism, genome-scale models, and metabolic engineering applications.

Metabolic Engineering: Pathways and Fluxes Log in to Mediaspace to watch this video

Explores the process of Metabolic Engineering, from genetic modifications to pathway analysis and genome-scale models.

Metabolic Engineering: Tools and Concepts Log in to Mediaspace to watch this video

Explores metabolic engineering tools, synthetic biology objectives, and metabolic pathway analysis for understanding cell physiology.

Systems Biology: Metabolism Modeling and Analysis Log in to Mediaspace to watch this video

Covers systems biology fundamentals, metabolism modeling, and analysis techniques, emphasizing metabolic flux distributions and omics integration.

Systems Biology of Metabolism Log in to Mediaspace to watch this video

Explores Systems Biology, metabolic pathways, genome-scale models, and bioinformatic tools for predictive biochemistry in bioproduction.

Genetic Circuits: Synthetic Biology Log in to Mediaspace to watch this video

Covers genetic circuits in synthetic biology, including metabolic engineering, lac operon regulation, and synthetic circuit design.

Metabolic Fluxes Analysis Log in to Mediaspace to watch this video

Explores metabolic pathways, flux balance analysis, genome-scale models, and underdetermined systems in understanding complex microbiomes.

Genetic Circuits: Design and Synthesis Log in to Mediaspace to watch this video

Explores the synthesis of genetic circuits, standardization of biological parts, and the importance of signal matching in genetic regulatory elements.

Metabolic Flux Balance Analysis Log in to Mediaspace to watch this video

Covers modeling and analyzing complex biological networks, focusing on metabolism and signaling, using techniques like flux balance analysis and kinetic modeling.

Chemical Biology: Metabolic Signaling Log in to Mediaspace to watch this video

Explores glycolysis, TCA cycle, Oxphos, and drug discovery in cancer.