Lecture

Hadamard Design: Introduction and Construction

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Description

This lecture covers the Hadamard design, Plackett-Burman design, full factorial design, normal plot analysis, and block setup to mitigate batch effects. It explains the construction of Plackett-Burman designs, circular permutations, least squares fit, projectivity, VIF optimization, and variance function.

Instructor

Jan Van Herle

Born in Antwerp, Belgium. In Switzerland since 1983. Became Swiss citizen in 2004 out of conviction of principles of democracy and bottom-up participation. No double nationality. Village Council Member for 2 five-year mandates in 2006-2016. 1987 : Chemist from Basel University (CH). 1988 : Post-graduate IT diploma from Basel Engineering School. 1989 : Industry internship ABB Baden (CH). 1990-1993 : PhD Thesis EPFL, on Solid Oxide Fuel Cell cathode reaction mechanisms. 1994-1995 : Japanese Postdoctoral Fellowship in Tsukuba, Japan, on ceramic powders. 1995-2000 : Researcher at EPFL, Dpt. Chemistry : project responsible in PPM2 (materials), FP4-BriteEuram, NEDO (Japan), Swiss Gas Union (CH, oxygen membranes). 1998-2000 : Masters in Energy Technology, EPFL. 2000 : Cofounder of HTceramix SA (EPFL spin-off), now based in Yverdon (14 employees). Taken over by SOLIDpower in 2007, now 250 employees with 70 MCHF raised. 2000 : 1st Assistant and lecturer at LENI (STI-IGM) : fuel cell group responsible, projects on biogas (Federal Energy Office), woodgas (CCEM), fuel cell stacking (CTI, FP6, FNS), ceramic separation membranes (COST, FNS), microtubes (STI Seed), stability/lifetime/reliability in fuel cells (Electricité de France, swisselectric research). Currently 4 Ph D theses ongoing, 14 theses concluded, of which 5 colateral with SB and IMX. M.E.R. since Nov 2008. Total funding raised so far >18 MCHF (50% as main applicant; 30% outside CH; 20% industry). Scientific output : >135 peer-reviewed publications, >120 conference papers, 40 invited presentations (8 keynotes), >70 granted proposals. Fluent in 5 languages (Dutch, French, German ( Swiss-german), English, Spanish).

Official source

Ontological neighbourhood

Statistics

Data analysis: Regression analysis

Related concepts (32)

Fractional factorial design

In statistics, fractional factorial designs are experimental designs consisting of a carefully chosen subset (fraction) of the experimental runs of a full factorial design. The subset is chosen so as to exploit the sparsity-of-effects principle to expose information about the most important features of the problem studied, while using a fraction of the effort of a full factorial design in terms of experimental runs and resources.

Least squares

The method of least squares is a standard approach in regression analysis to approximate the solution of overdetermined systems (sets of equations in which there are more equations than unknowns) by minimizing the sum of the squares of the residuals (a residual being the difference between an observed value and the fitted value provided by a model) made in the results of each individual equation. The most important application is in data fitting.

Total least squares

In applied statistics, total least squares is a type of errors-in-variables regression, a least squares data modeling technique in which observational errors on both dependent and independent variables are taken into account. It is a generalization of Deming regression and also of orthogonal regression, and can be applied to both linear and non-linear models. The total least squares approximation of the data is generically equivalent to the best, in the Frobenius norm, low-rank approximation of the data matrix.

Generalized least squares

In statistics, generalized least squares (GLS) is a method used to estimate the unknown parameters in a linear regression model when there is a certain degree of correlation between the residuals in the regression model. Least squares and weighted least squares may need to be more statistically efficient and prevent misleading inferences. GLS was first described by Alexander Aitken in 1935. In standard linear regression models one observes data on n statistical units.

Design of experiments

The design of experiments (DOE or DOX), also known as experiment design or experimental design, is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design introduces conditions that directly affect the variation, but may also refer to the design of quasi-experiments, in which natural conditions that influence the variation are selected for observation.

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