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This lecture covers the fundamentals of operational amplifiers (OPAMPs), including simplified schematics, non-idealities such as input bias and offset currents, and effects of input offset voltage. It also discusses common mode rejection ratio (CMRR), power supply rejection ratio (PSRR), frequency response, and macro-models. Furthermore, it explores instrumentation amplifiers, RC-active filters, and operational transconductance amplifiers (OTAs). The lecture emphasizes the impact of non-idealities on OPAMP performance and the design considerations for various filter configurations.