Lecture

Distinguishing the signal based on chemistry

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Description

This lecture covers the fundamentals of biomedical imaging, focusing on the role of the chemical environment in distinguishing signals. Topics include chemical shift effects, resonance frequencies, electron density, and the link between chemical shift and electronegativity.

In MOOC

Fundamentals of Biomedical Imaging: Magnetic Resonance Imaging (MRI)

This physics course covers the physical principles of major in vivo bio-imaging modalities. This course will focus on magnetic resonance imaging, also known as an MRI. In the first part of the course, the dynamic of spins in a magnetic field is described, leading to the essential notions of magnetic resonance (MR), excitation and relaxation. We will also discuss the basic mechanisms of image reconstruction, MR spectroscopy and functional MRI. You will learn how existing physical principles transcend into bi

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Related concepts (16)

Resonance

Resonance describes the phenomenon of increased amplitude that occurs when the frequency of an applied periodic force (or a Fourier component of it) is equal or close to a natural frequency of the system on which it acts. When an oscillating force is applied at a resonant frequency of a dynamic system, the system will oscillate at a higher amplitude than when the same force is applied at other, non-resonant frequencies. Frequencies at which the response amplitude is a relative maximum are also known as resonant frequencies or resonance frequencies of the system.

Acoustic resonance

Acoustic resonance is a phenomenon in which an acoustic system amplifies sound waves whose frequency matches one of its own natural frequencies of vibration (its resonance frequencies). The term "acoustic resonance" is sometimes used to narrow mechanical resonance to the frequency range of human hearing, but since acoustics is defined in general terms concerning vibrational waves in matter, acoustic resonance can occur at frequencies outside the range of human hearing.

Sympathetic resonance

Sympathetic resonance or sympathetic vibration is a harmonic phenomenon wherein a passive string or vibratory body responds to external vibrations to which it has a harmonic likeness. The classic example is demonstrated with two similarly-tuned tuning forks. When one fork is struck and held near the other, vibrations are induced in the unstruck fork, even though there is no physical contact between them. In similar fashion, strings will respond to the vibrations of a tuning fork when sufficient harmonic relations exist between them.

Medical imaging

Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities.

Electronegativity

Electronegativity, symbolized as χ, is the tendency for an atom of a given chemical element to attract shared electrons (or electron density) when forming a chemical bond. An atom's electronegativity is affected by both its atomic number and the distance at which its valence electrons reside from the charged nucleus. The higher the associated electronegativity, the more an atom or a substituent group attracts electrons.

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