Sample size determinationSample size determination is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample. In practice, the sample size used in a study is usually determined based on the cost, time, or convenience of collecting the data, and the need for it to offer sufficient statistical power.
Nonprobability samplingSampling is the use of a subset of the population to represent the whole population or to inform about (social) processes that are meaningful beyond the particular cases, individuals or sites studied. Probability sampling, or random sampling, is a sampling technique in which the probability of getting any particular sample may be calculated. In cases where external validity is not of critical importance to the study's goals or purpose, researchers might prefer to use nonprobability sampling.
Denaturation (biochemistry)In biochemistry, denaturation is a process in which proteins or nucleic acids lose the quaternary structure, tertiary structure, and secondary structure which is present in their native state, by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation or heat. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death.
Taq polymeraseTaq polymerase is a thermostable DNA polymerase I named after the thermophilic eubacterial microorganism Thermus aquaticus, from which it was originally isolated by Chien et al. in 1976. Its name is often abbreviated to Taq or Taq pol. It is frequently used in the polymerase chain reaction (PCR), a method for greatly amplifying the quantity of short segments of DNA. T. aquaticus is a bacterium that lives in hot springs and hydrothermal vents, and Taq polymerase was identified as an enzyme able to withstand the protein-denaturing conditions (high temperature) required during PCR.
Law of large numbersIn probability theory, the law of large numbers (LLN) is a theorem that describes the result of performing the same experiment a large number of times. According to the law, the average of the results obtained from a large number of trials should be close to the expected value and tends to become closer to the expected value as more trials are performed. The LLN is important because it guarantees stable long-term results for the averages of some random events.
GNU EmacsGNU Emacs is a free software text editor. It was created by GNU Project founder Richard Stallman, based on the Emacs editor developed for Unix operating systems. GNU Emacs has been a central component of the GNU project and a flagship project of the free software movement. Its tag line is "the extensible self-documenting text editor." In 1976, Stallman wrote the first Emacs (“Editor MACroS”), and in 1984, began work on GNU Emacs, to produce a free software alternative to the proprietary Gosling Emacs.
Normal extensionIn abstract algebra, a normal extension is an algebraic field extension L/K for which every irreducible polynomial over K which has a root in L, splits into linear factors in L. These are one of the conditions for algebraic extensions to be a Galois extension. Bourbaki calls such an extension a quasi-Galois extension. Let be an algebraic extension (i.e. L is an algebraic extension of K), such that (i.e. L is contained in an algebraic closure of K).
PNGPortable Network Graphics (PNG, officially pronounced pɪŋ , colloquially pronounced ˌpiːɛnˈdʒiː ) is a raster-graphics file that supports lossless data compression. PNG was developed as an improved, non-patented replacement for Graphics Interchange Format (GIF)—unofficially, the initials PNG stood for the recursive acronym "PNG's not GIF". PNG supports palette-based images (with palettes of 24-bit RGB or 32-bit RGBA colors), grayscale images (with or without an alpha channel for transparency), and full-color non-palette-based RGB or RGBA images.
PDFPortable Document Format (PDF), standardized as ISO 32000, is a developed by Adobe in 1992 to present documents, including text formatting and images, in a manner independent of application software, hardware, and operating systems. Based on the PostScript language, each PDF file encapsulates a complete description of a fixed-layout flat document, including the text, fonts, vector graphics, and other information needed to display it. PDF has its roots in "The Camelot Project" initiated by Adobe co-founder John Warnock in 1991.
Thermodynamic cycleA thermodynamic cycle consists of linked sequences of thermodynamic processes that involve transfer of heat and work into and out of the system, while varying pressure, temperature, and other state variables within the system, and that eventually returns the system to its initial state. In the process of passing through a cycle, the working fluid (system) may convert heat from a warm source into useful work, and dispose of the remaining heat to a cold sink, thereby acting as a heat engine.
Rankine cycleThe Rankine cycle is an idealized thermodynamic cycle describing the process by which certain heat engines, such as steam turbines or reciprocating steam engines, allow mechanical work to be extracted from a fluid as it moves between a heat source and heat sink. The Rankine cycle is named after William John Macquorn Rankine, a Scottish polymath professor at Glasgow University. Heat energy is supplied to the system via a boiler where the working fluid (typically water) is converted to a high pressure gaseous state (steam) in order to turn a turbine.
