Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Membrane Equilibrium Potential: Formulation and Models

In course

EE-519: Bioelectronics and biomedical microelectronics

The course covers the fundaments of bioelectronics and integrated microelectronics for biomedical and implantable systems. Issues and trade-offs at the circuit and systems levels of invasive microelectronic systems as well as their eluding designs, methods ...

Description

This lecture covers the concept of membrane equilibrium potential, including the Nernst equation and the Goldman-Hodgkin-Katz formulation. It explains the quantitative derivation of the equilibrium membrane potential and introduces the equivalent circuit model of the plasma membrane. The lecture also discusses the circuit model in resting state, graded response of the membrane potential based on cable theory, and compartment models of the membrane, including single and multi-compartment models. Furthermore, it delves into the organization of the nervous system, detailing the peripheral and central nervous systems, sensory and efferent divisions, and the role of the enteric nervous system.

This video is available exclusively on Mediaspace for a restricted audience. Please log in to MediaSpace to access it if you have the necessary permissions.

Watch on Mediaspace

Instructor

Alexandre Schmid

Alexandre Schmid received the M.Sc. degree in microengineering and the Ph.D. degree in electrical engineering from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in 1994 and 2000, respectively. Since 1994, he has been with the EPFL, working with the Integrated Systems Laboratory as a Research and Teaching Assistant, and with the Electronics Laboratories as a Postdoctoral Fellow. In 2002, he was a Senior Research Associate with the Microelectronic Systems Laboratory, where he has been conducting research in the fields of bioelectronic interfaces and implantable biomedical electronics, nonconventional signal processing and neuromorphic hardware, and reliability of nanoelectronic devices, and also teaches with the Microengineering and Electrical Engineering Departments of EPFL. Since 2011, he is a Maître d'Enseignement et de Recherche (MER) Faculty Member with EPFL. He is a coauthor of two books, Reliability of Nanoscale Circuits and Systems, Methodologies and Circuit Architectures, Springer, 2011, and Wireless Cortical Implantable Systems, Springer, 2013, and a coeditor of one book, as well as over 100 articles published in journals and conferences. Dr. Schmid has served as the General Chair of the Fourth International Conference on Nano-Networks in 2009 and has been serving as an Associate Editor of the Institute of Electrical, Information, and Communication Engineers Electronics Express since 2009.

Official source

Ontological neighbourhood

Biology

Anatomy: Neuroanatomy

Related concepts (32)

Membrane potential

Membrane potential (also transmembrane potential or membrane voltage) is the difference in electric potential between the interior and the exterior of a biological cell. That is, there is a difference in the energy required for electric charges to move from the internal to exterior cellular environments and vice versa, as long as there is no acquisition of kinetic energy or the production of radiation. The concentration gradients of the charges directly determine this energy requirement.

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts. It is a structure composed of nervous tissue positioned along the rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain.

Autonomic nervous system

The autonomic nervous system (ANS), formerly referred to as the vegetative nervous system, is a division of the nervous system that supplies internal organs, smooth muscle and glands. The autonomic nervous system is a control system that acts largely unconsciously and regulates bodily functions, such as the heart rate, its force of contraction, digestion, respiratory rate, pupillary response, urination, and sexual arousal. This system is the primary mechanism in control of the fight-or-flight response.

Peripheral nervous system

The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside the brain and the spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood–brain barrier, which leaves it exposed to toxins.

Enteric nervous system

The enteric nervous system (ENS) or intrinsic nervous system is one of the main divisions of the autonomic nervous system (ANS) and consists of a mesh-like system of neurons that governs the function of the gastrointestinal tract. It is capable of acting independently of the sympathetic and parasympathetic nervous systems, although it may be influenced by them. The ENS is nicknamed the "second brain". It is derived from neural crest cells.

Related lectures (34)

Membrane Potential: Electrical Properties of Neurons

Covers membrane potential, its measurement, and the equations governing ionic movement in neurons.

Modeling the electrical activity of the neuron MOOC: Simulation Neurocience

Explores the modeling of neuron electrical activity, including ion channels and concentrations, Nernst equation, and resting potential.

Neural Signals: Properties and Recordings

Explores the mechanical and electrical properties of neural tissues, including the brain and spinal cord, as well as the recording of neural signals using various techniques.

Biological Electricity: Action Potential Propagation and Modeling

Explores action potential propagation, membrane modeling, conductance, and encoding signals through action potential trains.

Cranial Nerves and Muscles of the Head: Anatomy Overview