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This lecture explores the importance of real-time sensory feedback in enhancing the control and functional impact of prosthetic hands. It covers the use of neuroengineering fundamentals to provide natural feedback through various methods, such as stimulating nerves in the stump, rerouting nerves, and stimulating the brain directly. The presentation delves into peripheral neural interfaces, first experiments with electrodes, sensory feedback with FINE electrodes, and the bidirectional control of hand prostheses. It discusses the invasiveness and selectivity of different neural interface types, as well as the results of long-term trials with neurocontrolled hand prostheses. The lecture also touches on the sensory loop, compliance recognition tasks, and the encoding of sensations through intracortical microstimulation.