Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.
Explores translation, mutations, ribosome function, protein folding, and degradation processes, emphasizing the genetic code's role in protein synthesis.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.
Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering spatial regulation, cell architecture, ER's role, and advanced techniques.
Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering translation in different cells and the ER's role in protein synthesis.
Covers the analysis of post-translational modifications using mass spectrometry, focusing on techniques, challenges, and the significance of phosphoproteomics.