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Lecture

Mechanical Measurement Techniques in Life Science

In course

ME-412: Experimental methods in engineering mechanics

This course gives an advanced treatment of experimental methods in the context of mechanics by way of example. Students will construct significant components of experimental apparatus, use their apparatus to collect data, interpret the resulting data, and ...

Description

This lecture covers various mechanical measurement techniques used in life sciences, including microscopy, optical traps, magnetic tweezers, and deformable beads. The slides present information on the relative sizes of biological organisms and chemical species, popular microscopy techniques, optical trapping theory and practice, and the quantification of cell-scale stress in zebrafish development.

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Instructor

John Martin Kolinski

Dr. Kolinski studied Applied Mathematics (Sc.M.) and Applied Physics (Ph.D.) at Harvard University, completing a PhD under the supervision of L. Mahadevan and Shmuel Rubinstein on the role of air in droplet impact. John did his post-doc at the Hebrew University of Jerusalem in Israel supported by the Fulbright post-doctoral fellowship. At HUJI, he worked on interfacial instabilities in soft matter in the labs of Eran Sharon and Jay Fineberg. John continues his research into interfacial mechanics at EPFL in EMSI, his newly founded laboratory for the study of Engineering Mechanics of Soft Interfaces.

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Related concepts (19)

Quantifier (logic)

In logic, a quantifier is an operator that specifies how many individuals in the domain of discourse satisfy an open formula. For instance, the universal quantifier in the first order formula expresses that everything in the domain satisfies the property denoted by . On the other hand, the existential quantifier in the formula expresses that there exists something in the domain which satisfies that property. A formula where a quantifier takes widest scope is called a quantified formula.

Price elasticity of demand

A good's price elasticity of demand (, PED) is a measure of how sensitive the quantity demanded is to its price. When the price rises, quantity demanded falls for almost any good, but it falls more for some than for others. The price elasticity gives the percentage change in quantity demanded when there is a one percent increase in price, holding everything else constant. If the elasticity is −2, that means a one percent price rise leads to a two percent decline in quantity demanded.

Universal quantification

In mathematical logic, a universal quantification is a type of quantifier, a logical constant which is interpreted as "given any", "for all", or "for any". It expresses that a predicate can be satisfied by every member of a domain of discourse. In other words, it is the predication of a property or relation to every member of the domain. It asserts that a predicate within the scope of a universal quantifier is true of every value of a predicate variable.

Elasticity (economics)

In economics, elasticity measures the responsiveness of one economic variable to a change in another. If the price elasticity of the demand of something is -2, a 10% increase in price causes the quantity demanded to fall by 20%. Elasticity in economics provides an understanding of changes in the behavior of the buyers and sellers with price changes. There are two types of elasticity for demand and supply, one is inelastic demand and supply and other one is elastic demand and supply.

Cross elasticity of demand

In economics, the cross (or cross-price) elasticity of demand measures the effect of changes in the price of one good on the quantity demanded of another good. This reflects the fact that the quantity demanded of good is dependent on not only its own price (price elasticity of demand) but also the price of other "related" good. The cross elasticity of demand is calculated as the ratio between the percentage change of the quantity demanded for a good and the percentage change in the price of another good, ceteris paribus:The sign of the cross elasticity indicates the relationship between two goods.

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