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This lecture covers the principles of neural signal processing, focusing on imaging techniques such as MRI and fMRI. Topics include radio wave imaging, Fourier transforms, k-space, pulse sequences, and fast acquisitions. The instructor discusses the importance of understanding structural and functional connectivity, as well as the validation of hemodynamic response functions. Various imaging methods like PET and fNIRS are explained, along with their clinical applications. The lecture concludes with a case study on topographic organization in the brain.