Lecture

Polymers and Particles: Printing, Structures, and Applications

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In course

MSE-471: Biomaterials (pour MX)

The course introduces the main classes of biomaterials used in the biomedical field. The interactions with biological environment are discussed and challenges highlighted. State of the art examples per type of material are discussed. Students will engineer ...

Description

This lecture explores the use of polymers in 3D printing, focusing on shear thinning behavior and viscoelastic properties for printing biomaterials. It delves into the functional unit of a nephron and the 3D printing of a kidney model. The discussion extends to the printing of hollow structures, shape memory polymers, programmable polymers using DNA structures, and reprogramming DNA interactions. The lecture also covers nanoparticles and microparticles, cellular uptake pathways, and the design of controlled drug release systems. Various types of nanoparticles, including lipid-based, gold-based, and DNA-based nanoparticles, are discussed, along with their structures and applications. The lecture concludes with a comparison between nanoparticles and microparticles in drug delivery systems.

Instructor

Maartje Martina Cornelia Bastings

Expertise Can we use structural material properties on the nanoscale to engineer selective interactions at the bio-interface?The goal of the Programmable Biomaterials Lab is to understand the molecular design rules behind selective multivalent interactions at the bio-interface. We use DNA as engineering tool to explore the importance of structural mechanics and precise control of valency and patterns on directional interactions and self-assembly. Expertise Can we use structural material properties on the na

Official source

Ontological neighbourhood

Chemical engineering

Nanotechnology: Topics in nanotechnology

Related concepts (28)

Silver nanoparticle

Silver nanoparticles are nanoparticles of silver of between 1 nm and 100 nm in size. While frequently described as being 'silver' some are composed of a large percentage of silver oxide due to their large ratio of surface to bulk silver atoms. Numerous shapes of nanoparticles can be constructed depending on the application at hand. Commonly used silver nanoparticles are spherical, but diamond, octagonal, and thin sheets are also common. Their extremely large surface area permits the coordination of a vast number of ligands.

Nanoparticle

A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead.

Colloidal gold

Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. The colloid is coloured usually either wine red (for spherical particles less than 100 nm) or blue-purple (for larger spherical particles or nanorods). Due to their optical, electronic, and molecular-recognition properties, gold nanoparticles are the subject of substantial research, with many potential or promised applications in a wide variety of areas, including electron microscopy, electronics, nanotechnology, materials science, and biomedicine.

Platinum nanoparticle

Platinum nanoparticles are usually in the form of a suspension or colloid of nanoparticles of platinum in a fluid, usually water. A colloid is technically defined as a stable dispersion of particles in a fluid medium (liquid or gas). Spherical platinum nanoparticles can be made with sizes between about 2 and 100 nanometres (nm), depending on reaction conditions. Platinum nanoparticles are suspended in the colloidal solution of brownish-red or black color. Nanoparticles come in wide variety of shapes including spheres, rods, cubes, and tetrahedra.

Nanotechnology

Nanotechnology, often shortened to nanotech, is the use of matter on atomic, molecular, and supramolecular scales for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm).

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