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This lecture covers the concept of spin qubits in quantum dots, including their initialization, read-out, and manipulation using techniques such as ESR and SWAP. It also discusses real-time single-electron detection and pulse-induced tunneling for tunneling response. Energy-selective readout and the measurement of T₁ relaxation time are explained, along with spin relaxation mechanisms in quantum dots. The lecture concludes with coherent control of a single electron spin and the spin-orbit interaction mechanism involving Rashba and Dresselhaus terms.