Lecture

Analog Circuits for Biochip: Biosensors & Temperature

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In course

EE-518: Analog circuits for biochip

Introduction to analog CMOS design for Remote Biosensors on Chip. Understanding and designing of active and remotely powered biosensing systems. Basic understanding of the wireless transmission of the obtained signals. ...

Description

This lecture covers the design of analog circuits for biochips, focusing on biosensors and temperature compensation. Topics include op-amp configurations, transimpedance amplifiers, current mirrors, and the PTAT method for temperature sensing. The instructor discusses the importance of dynamic range, switch capacitors, and multiplexing techniques for biochip applications.

Instructors (4)

Catherine Dehollain

She got the Master Degree in Electrical Engineering in 1982 from EPFL. Then, she worked in Geneva up to 1990 as a Senior Design Engineer in telecommunications at the European research center of Motorola. From 1990 up to 1995, she did her PhD thesis at the Chaire des Circuits et Systemes at EPFL in the domain of impedance broadband matching circuits. Since 1995, she is responsible at EPFL for the RFIC group. She has participated to different Swiss research projects as well as European projects dedicated to data communication of sensors nodes (e.g. MuMoR, Minami European projects) as well as remote powering of sensor nodes. Her main domains of interest are telecom applications (e.g. Impulse radio Ultra-Wide Band, super-regenerative receivers, RFIDs)as well as biomedical applications. She has been the coordinator of European projects (e.g. FP6 SUPREGE, FP7 Ultrasponder)and of Swiss projects (e.g. CAPED CTI project, NEURO-IC SNF project).

Alexandre Schmid

Alexandre Schmid received the M.Sc. degree in microengineering and the Ph.D. degree in electrical engineering from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in 1994 and 2000, respectively. Since 1994, he has been with the EPFL, working with the Integrated Systems Laboratory as a Research and Teaching Assistant, and with the Electronics Laboratories as a Postdoctoral Fellow. In 2002, he was a Senior Research Associate with the Microelectronic Systems Laboratory, where he has been conducting research in the fields of bioelectronic interfaces and implantable biomedical electronics, nonconventional signal processing and neuromorphic hardware, and reliability of nanoelectronic devices, and also teaches with the Microengineering and Electrical Engineering Departments of EPFL. Since 2011, he is a Maître d'Enseignement et de Recherche (MER) Faculty Member with EPFL. He is a coauthor of two books, Reliability of Nanoscale Circuits and Systems, Methodologies and Circuit Architectures, Springer, 2011, and Wireless Cortical Implantable Systems, Springer, 2013, and a coeditor of one book, as well as over 100 articles published in journals and conferences. Dr. Schmid has served as the General Chair of the Fourth International Conference on Nano-Networks in 2009 and has been serving as an Associate Editor of the Institute of Electrical, Information, and Communication Engineers Electronics Express since 2009.

Sandro Carrara

Official source

Ontological neighbourhood

Physics

Electromagnetism: Electrical networks

Related concepts (32)

Frequency compensation

In electronics engineering, frequency compensation is a technique used in amplifiers, and especially in amplifiers employing negative feedback. It usually has two primary goals: To avoid the unintentional creation of positive feedback, which will cause the amplifier to oscillate, and to control overshoot and ringing in the amplifier's step response. It is also used extensively to improve the bandwidth of single pole systems.

Decoupling capacitor

In electronics, a decoupling capacitor is a capacitor used to decouple (i.e. prevent electrical energy from transferring to) one part of a circuit from another. Noise caused by other circuit elements is shunted through the capacitor, reducing its effect on the rest of the circuit. For higher frequencies, an alternative name is bypass capacitor as it is used to bypass the power supply or other high-impedance component of a circuit. Active devices of an electronic system (e.g.

Motor capacitor

A motor capacitor is an electrical capacitor that alters the current to one or more windings of a single-phase alternating-current induction motor to create a rotating magnetic field. There are two common types of motor capacitors, start capacitor and run capacitor (including a dual run capacitor). Motor capacitors are used with single-phase electric motors that are in turn used to drive air conditioners, hot tub/jacuzzi spa pumps, powered gates, large fans or forced-air heat furnaces for example.

Operational amplifier

An operational amplifier (often op amp or opamp) is a DC-coupled high-gain electronic voltage amplifier with a differential input and, usually, a single-ended output. In this configuration, an op amp produces an output potential (relative to circuit ground) that is typically 100,000 times larger than the potential difference between its input terminals. The operational amplifier traces its origin and name to analog computers, where they were used to perform mathematical operations in linear, non-linear, and frequency-dependent circuits.

Capacitor types

Capacitors are manufactured in many styles, forms, dimensions, and from a large variety of materials. They all contain at least two electrical conductors, called plates, separated by an insulating layer (dielectric). Capacitors are widely used as parts of electrical circuits in many common electrical devices. Capacitors, together with resistors and inductors, belong to the group of passive components in electronic equipment.

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Sandro Carrara is an IEEE Fellow for his outstanding record of accomplishments in the field of design of nanoscale biological CMOS sensors. He is also the recipient of the IEEE Sensors Council Technical Achievement Award in 2016 for his leadership in the emerging area of co-design in Bio/Nano/CMOS interfaces. He is a Professor of the EPFL in Lausanne (Switzerland), and head of the "Bio/CMOS Interfaces" (BCI) research group. He is former professor of optical and electrical biosensors at the Department of Electrical Engineering and Biophysics (DIBE) of the University of Genoa (Italy) and former professor of nanobiotechnology at the University of Bologna (Italy). He holds a PhD in Biochemistry & Biophysics from University of Padua (Italy), a Master degree in Physics from University of Genoa (Italy), and a diploma in Electronics from National Institute of Technology in Albenga (Italy). His scientific interests are on electrical phenomena of nano-bio-structured films, and include CMOS design of biochips based on proteins and DNA. Along his carrier, he published 7 books, one as author with Springer on Bio/CMOS interfaces and, more recently, a Handbook of Bioelectronics with Cambridge University Press. He has more than 250 scientific publications and is author of 13 patents. He is now Editor-in-Chief of the IEEE Sensors Journal, the largest journal among 2019 IEEE publications; he is also founder and Editor-in-Chief of the journal BioNanoScience by Springer, and Associate Editor of IEEE Transactions on Biomedical Circuits and Systems. He is a member of the IEEE Sensors Council and his Executive Committee. He was a member of the Board of Governors (BoG) of the IEEE Circuits And Systems Society (CASS). He has been appointed as IEEE Sensors Council Distinguished Lecturer for the years 2017-2019, and CASS Distinguished Lecturer for the years 2013-2014. His work received several international recognitions: several Top-25 Hottest-Articles (2004, 2005, 2008, 2009, and two times in 2012) published in highly ranked international journals such as Biosensors and Bioelectronics, Sensors and Actuators B, IEEE Sensors journal, and Thin Solid Films; a NATO Advanced Research Award in 1996 for the original contribution to the physics of single-electron conductivity in nano-particles; six Best Paper Awards at the IEEE Sensors Conference 2019 (Montreal) in 2019, Conferences IEEE NGCAS in 2017 (Genoa), MOBIHEALTH in 2016 (Milan), IEEE PRIME in 2015 (Glasgow), in 2010 (Berlin), and in 2009 (Cork); three Best Poster Awards at the EMBEC Conference in 2017 (Tampere, Finland), Nanotera workshop in 2011 (Bern), and NanoEurope Symposium in 2009 (Rapperswil). He also received the Best Referees Award from the journal Biosensor and Bioelectronics in 2006. From 1997 to 2000, he was a member of an international committee at the ELETTRA Synchrotron in Trieste. From 2000 to 2003, he was scientific leader of a National Research Program (PNR) in the filed of Nanobiotechnology. He was an internationally esteemed expert of the evaluation panel of the Academy of Finland in a research program for the years 2010-2013. He has been the General Chairman of the Conference IEEE BioCAS 2014, the premier worldwide international conference in the area of circuits and systems for biomedical applications

Related concepts (32)

Frequency compensation

Decoupling capacitor

Motor capacitor

Operational amplifier

Capacitor types