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This lecture explores the movement of motile unicellular organisms like Euglena gracilis and the concept of morphing structures inspired by their motion. The instructor discusses the active transport mechanisms in biological micron-scale machines, focusing on flagellar swimming and cell deformations. The lecture delves into the transition from flagellar swimming to amoeboid motion triggered by confinement, raising questions about decision-making processes in brainless organisms. Additionally, the concept of shape morphing by sliding is introduced, highlighting its versatility and compatibility with various actuation methods.