Explores Chemical Biology's interdisciplinary nature, enzyme inhibition, genetic methods, and metabolic regulation, highlighting its real-world relevance through recent Nobel Prize contributions.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
