H2 receptor antagonistDISPLAYTITLE:H2 receptor antagonist H2 antagonists, sometimes referred to as H2RAs and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and gastroesophageal reflux disease.
Ribonuclease HRibonuclease H (abbreviated RNase H or RNH) is a family of non-sequence-specific endonuclease enzymes that catalyze the cleavage of RNA in an RNA/DNA substrate via a hydrolytic mechanism. Members of the RNase H family can be found in nearly all organisms, from bacteria to archaea to eukaryotes. The family is divided into evolutionarily related groups with slightly different substrate preferences, broadly designated ribonuclease H1 and H2. The human genome encodes both H1 and H2.
Histone H2AHistone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. The other histone proteins are: H1, H2B, H3 and H4. Histones are proteins that package DNA into nucleosomes. Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed of at least one of each core histones per 100 base pairs of DNA. There are five families of histones known to date; these histones are termed H1/H5, H2A, H2B, H3, and H4.
BIBO stabilityIn signal processing, specifically control theory, bounded-input, bounded-output (BIBO) stability is a form of stability for signals and systems that take inputs. If a system is BIBO stable, then the output will be bounded for every input to the system that is bounded. A signal is bounded if there is a finite value such that the signal magnitude never exceeds , that is For discrete-time signals: For continuous-time signals: For a continuous time linear time-invariant (LTI) system, the condition for BIBO stability is that the impulse response, , be absolutely integrable, i.
Z-transformIn mathematics and signal processing, the Z-transform converts a discrete-time signal, which is a sequence of real or complex numbers, into a complex frequency-domain (z-domain or z-plane) representation. It can be considered as a discrete-time equivalent of the Laplace transform (s-domain). This similarity is explored in the theory of time-scale calculus. Whereas the continuous-time Fourier transform is evaluated on the Laplace s-domain's imaginary line, the discrete-time Fourier transform is evaluated over the unit circle of the z-domain.
Pole–zero plotIn mathematics, signal processing and control theory, a pole–zero plot is a graphical representation of a rational transfer function in the complex plane which helps to convey certain properties of the system such as: Stability Causal system / anticausal system Region of convergence (ROC) Minimum phase / non minimum phase A pole-zero plot shows the location in the complex plane of the poles and zeros of the transfer function of a dynamic system, such as a controller, compensator, sensor, equalizer, filter,
Stable distributionIn probability theory, a distribution is said to be stable if a linear combination of two independent random variables with this distribution has the same distribution, up to location and scale parameters. A random variable is said to be stable if its distribution is stable. The stable distribution family is also sometimes referred to as the Lévy alpha-stable distribution, after Paul Lévy, the first mathematician to have studied it. Of the four parameters defining the family, most attention has been focused on the stability parameter, (see panel).
DNA barcodingDNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that by comparison with a reference library of such DNA sections (also called "sequences"), an individual sequence can be used to uniquely identify an organism to species, just as a supermarket scanner uses the familiar black stripes of the UPC barcode to identify an item in its stock against its reference database.
Cultured meatCultured meat (also known as cultivated meat among other names) is a form of cellular agriculture where meat is produced by culturing animal cells in vitro. Cultured meat is produced using tissue engineering techniques pioneered in regenerative medicine. Jason Matheny popularized the concept in the early 2000s after he co-authored a paper on cultured meat production and created New Harvest, the world's first nonprofit organization dedicated to in-vitro meat research.
École Polytechnique Fédérale de LausanneThe École polytechnique fédérale de Lausanne (EPFL; English: Swiss Federal Institute of Technology in Lausanne; Eidgenössische Technische Hochschule Lausanne) is a public research university in Lausanne, Switzerland. Established in 1853, EPFL has placed itself as a university specializing in engineering and natural sciences. EPFL is part of the ETH Domain, which is directly dependent on the Federal Department of Economic Affairs, Education and Research.
Convergence of random variablesIn probability theory, there exist several different notions of convergence of random variables. The convergence of sequences of random variables to some limit random variable is an important concept in probability theory, and its applications to statistics and stochastic processes. The same concepts are known in more general mathematics as stochastic convergence and they formalize the idea that a sequence of essentially random or unpredictable events can sometimes be expected to settle down into a behavior that is essentially unchanging when items far enough into the sequence are studied.
Pointwise convergenceIn mathematics, pointwise convergence is one of various senses in which a sequence of functions can converge to a particular function. It is weaker than uniform convergence, to which it is often compared. Suppose that is a set and is a topological space, such as the real or complex numbers or a metric space, for example. A net or sequence of functions all having the same domain and codomain is said to converge pointwise to a given function often written as if (and only if) The function is said to be the pointwise limit function of the Sometimes, authors use the term bounded pointwise convergence when there is a constant such that .
Enterprise resource planningEnterprise resource planning (ERP) is the integrated management of main business processes, often in real-time and mediated by software and technology. ERP is usually referred to as a category of business management software—typically a suite of integrated applications—that an organization can use to collect, store, manage and interpret data from many business activities. ERP systems can be local-based or cloud-based. Cloud-based applications have grown in recent years due to the increased efficiencies arising from information being readily available from any location with Internet access.
PittsburghPittsburgh (ˈpɪtsbɜːrɡ ) is a city in the Commonwealth of Pennsylvania and the county seat of Allegheny County. It is the most populous city in both Allegheny County and Western Pennsylvania, the second-most populous city in Pennsylvania after Philadelphia, and the 68th-most populous city in the U.S. with a population of 302,971 as of the 2020 census. It is the largest city of the Greater Pittsburgh metropolitan area of Western Pennsylvania; its population of 2.
Alt-rightThe alt-right (abbreviated from alternative right) is a far-right, white nationalist, white supremacist, anti-LGBT, anti-immigration and antifeminist movement. A largely online phenomenon, the alt-right originated in the United States during the late 2000s before increasing in popularity and establishing a presence in other countries during the mid-2010s, and has been declining since 2017. The term is ill-defined and has been used in different ways by academics, journalists, media commentators, and alt-right members themselves.
AppalachiaAppalachia (ˌæpəˈlætʃə,-leɪtʃə,-leɪʃə) is a socio-economic region located in the central and southern sections of the Appalachian Mountains of the Eastern United States. It stretches from the western Catskill Mountains in the east end of the Southern Tier of New York state west and south into Pennsylvania, continuing on through the Blue Ridge Mountains into northern Georgia, and through the Great Smoky Mountains from North Carolina into Tennessee and northern Alabama. In 2020, the region was home to an estimated 26.
OmOm (or Aum) (; ॐ, ओम्) is a symbol representing a sacred sound, syllable, mantra, and an invocation in Hinduism. Its written representation is one of the most important symbols of Hinduism. It is variously said to be the essence of the supreme Absolute, consciousness, Ātman, Brahman, or the cosmic world. In Indic traditions, Om serves as a sonic representation of the divine, a standard of Vedic authority and a central aspect of soteriological doctrines and practices.
ArtArt is a diverse range of human activity, and resulting product, that involves creative or imaginative talent expressive of technical proficiency, beauty, emotional power, or conceptual ideas. There is no generally agreed definition of what constitutes art, and its interpretation has varied greatly throughout history and across cultures. In the Western tradition, the three classical branches of visual art are painting, sculpture, and architecture.
HangulThe Korean alphabet, known as Hangul (ˈhɑːnguːl ; ) in South Korea and Chosŏn'gŭl () in North Korea, is the modern official writing system for the Korean language. The letters for the five basic consonants reflect the shape of the speech organs used to pronounce them, and they are systematically modified to indicate phonetic features; similarly, the vowel letters are systematically modified for related sounds, making Hangul a featural writing system.
Outsider artOutsider art is art made by self-taught or supposedly naïve artists with typically little or no contact with the conventions of the art worlds. In many cases, their work is discovered only after their deaths. Often, outsider art illustrates extreme mental states, unconventional ideas, or elaborate fantasy worlds. The term outsider art was coined in 1972 as the title of a book by art critic Roger Cardinal. It is an English equivalent for art brut (aʁ bʁyt, "raw art" or "rough art"), a label created in the 1940s by French artist Jean Dubuffet to describe art created outside the boundaries of official culture.
