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This lecture covers the behavior of non-polarized electrodes where current flows freely through the electrode-electrolyte interface, leading to redox reactions. It also discusses the use of Ag-AgCl electrodes in medical instrumentation, their conduction properties, and applications in measuring biopotentials. The concept of polarized electrodes is introduced, highlighting their inability to allow charge transfer across the interface. The lecture concludes with a detailed model of electrodes, impedance considerations, and electrode-skin interfaces. Various types of ECG electrodes and their applications in monitoring and stimulation are also explored.