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Lecture

Radiotherapy: Basics & Classical Methods

In course

PHYS-450: Radiation biology, protection and applications

This is an introductory course in radiation physics that aims at providing students with a foundation in radiation protection and with information about the main applications of radioactive sources/substances in the industry. The course includes presentati ...

Description

This lecture covers the basics and classical methods of radiotherapy, focusing on the application of ionizing radiation to fight cancer. Topics include the biological principles of carcinogenesis, types of radiotherapy techniques such as external beam and brachytherapy, and the use of radiosensitizers and radioprotectors. The lecture also discusses the characteristics of cancerous cells, cell response to radiation, and the importance of fractionation in radiotherapy strategies.

Instructors (2)

Pavel Frajtag

Oskari Ville Pakari

Official source

Ontological neighbourhood

Health sciences

Radiology: Topics in radiology

Biology

Cell biology: Cancer

Related concepts (32)

Radiation therapy

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer).

Radiobiology

Radiobiology (also known as radiation biology, and uncommonly as actinobiology) is a field of clinical and basic medical sciences that involves the study of the action of ionizing radiation on living things, especially health effects of radiation. Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Its most common impact is the induction of cancer with a latent period of years or decades after exposure.

External beam radiotherapy

External beam radiation therapy (EBRT) is a compound word that refers to the use of a collimated beam of ionizing radiation from outside the body to treat a disease. external—from outside the body, beam—shaped by collimation, radiation—ionizing radiation, therapy—used to treat disease The word teletherapy has the same meaning as external beam radiation therapy with the tele- empahasizing that it is treatment from a distance. Radiation and therapy are commonly shortened into the portmanteau radiotherapy.

Acute radiation syndrome

Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. Symptoms can start within an hour of exposure, and can last for several months. Early symptoms are usually nausea, vomiting and loss of appetite. In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follow.

Ionizing radiation

Ionizing radiation (or ionising radiation), including nuclear radiation, consists of subatomic particles or electromagnetic waves that have sufficient energy to ionize atoms or molecules by detaching electrons from them. Some particles can travel up to 99% of the speed of light, and the electromagnetic waves are on the high-energy portion of the electromagnetic spectrum. Gamma rays, X-rays, and the higher energy ultraviolet part of the electromagnetic spectrum are ionizing radiation, whereas the lower energy ultraviolet, visible light, nearly all types of laser light, infrared, microwaves, and radio waves are non-ionizing radiation.

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