Metabolic pathwayIn biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes. In most cases of a metabolic pathway, the product of one enzyme acts as the substrate for the next. However, side products are considered waste and removed from the cell. These enzymes often require dietary minerals, vitamins, and other cofactors to function.
Flux (metabolism)Flux, or metabolic flux is the rate of turnover of molecules through a metabolic pathway. Flux is regulated by the enzymes involved in a pathway. Within cells, regulation of flux is vital for all metabolic pathways to regulate the pathway's activity under different conditions. Flux is therefore of great interest in metabolic network modelling, where it is analysed via flux balance analysis and metabolic control analysis.
Metabolic network modellingMetabolic network modelling, also known as metabolic network reconstruction or metabolic pathway analysis, allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. A reconstruction breaks down metabolic pathways (such as glycolysis and the citric acid cycle) into their respective reactions and enzymes, and analyzes them within the perspective of the entire network.
Metabolic networkA metabolic network is the complete set of metabolic and physical processes that determine the physiological and biochemical properties of a cell. As such, these networks comprise the chemical reactions of metabolism, the metabolic pathways, as well as the regulatory interactions that guide these reactions. With the sequencing of complete genomes, it is now possible to reconstruct the network of biochemical reactions in many organisms, from bacteria to human.
COMMAND.COMCOMMAND.COM is the default command-line interpreter for MS-DOS, Windows 95, Windows 98 and Windows Me. In the case of DOS, it is the default user interface as well. It has an additional role as the usual first program run after boot (init process), hence being responsible for setting up the system by running the AUTOEXEC.BAT configuration file, and being the ancestor of all processes. COMMAND.COM's successor on OS/2 and Windows NT systems is cmd.exe, although COMMAND.
Cd (command)The command, also known as (change directory), is a command-line shell command used to change the current working directory in various operating systems. It can be used in shell scripts and s. The command has been implemented in operating systems such as Unix, DOS, IBM OS/2, MetaComCo TRIPOS, AmigaOS (where if a bare path is given, cd is implied), Microsoft Windows, ReactOS, and Linux. On MS-DOS, it is available in versions 2 and later. DR DOS 6.0 also includes an implementation of the and commands.
ThermodynamicsThermodynamics is a branch of physics that deals with heat, work, and temperature, and their relation to energy, entropy, and the physical properties of matter and radiation. The behavior of these quantities is governed by the four laws of thermodynamics which convey a quantitative description using measurable macroscopic physical quantities, but may be explained in terms of microscopic constituents by statistical mechanics.
CLS (command)In computing, CLS (for clear screen) is a command used by the command-line interpreters COMMAND.COM and cmd.exe on DOS, Digital Research FlexOS, IBM OS/2, Microsoft Windows and ReactOS operating systems to clear the screen or console window of commands and any output generated by them. It does not clear the user's history of commands, however. The command is also available in the DEC RT-11 operating system, in the open-source MS-DOS emulator DOSBox and in the EFI shell.
List of DOS commandsThis article presents a list of commands used by DOS operating systems, especially as used on x86-based IBM PC compatibles (PCs). Other DOS operating systems are not part of the scope of this list. In DOS, many standard system commands were provided for common tasks such as listing files on a disk or moving files. Some commands were built into the command interpreter, others existed as external commands on disk. Over the several generations of DOS, commands were added for the additional functions of the operating system.
Path (computing)A path is a string of characters used to uniquely identify a location in a directory structure. It is composed by following the directory tree hierarchy in which components, separated by a delimiting character, represent each directory. The delimiting character is most commonly the slash ("/"), the backslash character (""), or colon (":"), though some operating systems may use a different delimiter. Paths are used extensively in computer science to represent the directory/file relationships common in modern operating systems and are essential in the construction of Uniform Resource Locators (URLs).
Laws of thermodynamicsThe laws of thermodynamics are a set of scientific laws which define a group of physical quantities, such as temperature, energy, and entropy, that characterize thermodynamic systems in thermodynamic equilibrium. The laws also use various parameters for thermodynamic processes, such as thermodynamic work and heat, and establish relationships between them. They state empirical facts that form a basis of precluding the possibility of certain phenomena, such as perpetual motion.
MATLABMATLAB (an abbreviation of "MATrix LABoratory") is a proprietary multi-paradigm programming language and numeric computing environment developed by MathWorks. MATLAB allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other languages. Although MATLAB is intended primarily for numeric computing, an optional toolbox uses the MuPAD symbolic engine allowing access to symbolic computing abilities.
Dir (command)In computing, dir (directory) is a command in various computer operating systems used for and directory listing. It is one of the basic commands to help navigate the . The command is usually implemented as an internal command in the command-line interpreter (shell). On some systems, a more graphical representation of the directory structure can be displayed using the tree command.
File ExplorerFile Explorer, previously known as Windows Explorer, is a application and default desktop environment that is included with releases of the Microsoft Windows operating system from Windows 95 onwards. It provides a graphical user interface for accessing the s. It is also the component of the operating system that presents many user interface items on the screen such as the taskbar and desktop. Controlling the computer is possible without File Explorer running (for example, the command in Task Manager on NT-derived versions of Windows will function without it, as will commands typed in a command prompt window).
Home directoryA home directory is a on a multi-user operating system containing for a given user of the system. The specifics of the home directory (such as its name and location) are defined by the operating system involved; for example, Linux / BSD () systems use /home/ or /usr/home/ and Windows systems between 2000 and Server 2003 keep home directories in a folder named Documents and Settings. A user's home directory is intended to contain that user's files; including text documents, music, pictures, videos, etc.
Chemical thermodynamicsChemical thermodynamics is the study of the interrelation of heat and work with chemical reactions or with physical changes of state within the confines of the laws of thermodynamics. Chemical thermodynamics involves not only laboratory measurements of various thermodynamic properties, but also the application of mathematical methods to the study of chemical questions and the spontaneity of processes. The structure of chemical thermodynamics is based on the first two laws of thermodynamics.
Flux balance analysisFlux balance analysis (FBA) is a mathematical method for simulating metabolism in genome-scale reconstructions of metabolic networks. In comparison to traditional methods of modeling, FBA is less intensive in terms of the input data required for constructing the model. Simulations performed using FBA are computationally inexpensive and can calculate steady-state metabolic fluxes for large models (over 2000 reactions) in a few seconds on modern personal computers.
Non-equilibrium thermodynamicsNon-equilibrium thermodynamics is a branch of thermodynamics that deals with physical systems that are not in thermodynamic equilibrium but can be described in terms of macroscopic quantities (non-equilibrium state variables) that represent an extrapolation of the variables used to specify the system in thermodynamic equilibrium. Non-equilibrium thermodynamics is concerned with transport processes and with the rates of chemical reactions.
Second law of thermodynamicsThe second law of thermodynamics is a physical law based on universal experience concerning heat and energy interconversions. One simple statement of the law is that heat always moves from hotter objects to colder objects (or "downhill"), unless energy in some form is supplied to reverse the direction of heat flow. Another definition is: "Not all heat energy can be converted into work in a cyclic process." The second law of thermodynamics in other versions establishes the concept of entropy as a physical property of a thermodynamic system.
First law of thermodynamicsThe first law of thermodynamics is a formulation of the law of conservation of energy, adapted for thermodynamic processes. A simple formulation is: "The total energy in a system remains constant, although it may be converted from one form to another." Another common phrasing is that "energy can neither be created nor destroyed". While there are many subtleties and implications that may be more precisely captured in more complex formulations, this is the essential principle of the First Law.
