Lecture

Biofabrication and Bioprinting

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Description

This lecture covers the concepts of biofabrication and bioprinting, including the automated generation of biologically functional products from living cells, bioactive molecules, and biomaterials. It explains the building blocks in biofabrication, various bioprinting technologies like inkjet printing and extrusion, and the challenges and advancements in creating complex structures. The lecture also delves into the use of sacrificial materials, viscosity enhancers, and multimaterial printing for creating intricate tissue constructs. Furthermore, it discusses in vivo and in situ printing, hybrid printing with dECM-derived bioinks, and the future prospects of bioprinting as a clinically-ready technology.

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Related concepts (32)

Digital printing

Digital printing is a method of printing from a digital-based image directly to a variety of media. It usually refers to professional printing where small-run jobs from desktop publishing and other digital sources are printed using large-format and/or high-volume laser or inkjet printers. Digital printing has a higher cost per page than more traditional offset printing methods, but this price is usually offset by avoiding the cost of all the technical steps required to make printing plates.

Linear complex structure

In mathematics, a complex structure on a real vector space V is an automorphism of V that squares to the minus identity, −I. Such a structure on V allows one to define multiplication by complex scalars in a canonical fashion so as to regard V as a complex vector space. Every complex vector space can be equipped with a compatible complex structure, however, there is in general no canonical such structure. Complex structures have applications in representation theory as well as in complex geometry where they play an essential role in the definition of almost complex manifolds, by contrast to complex manifolds.

Generalized complex structure

In the field of mathematics known as differential geometry, a generalized complex structure is a property of a differential manifold that includes as special cases a complex structure and a symplectic structure. Generalized complex structures were introduced by Nigel Hitchin in 2002 and further developed by his students Marco Gualtieri and Gil Cavalcanti.

Tissue engineering

Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. Tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose but is not limited to applications involving cells and tissue scaffolds.

3D printing

3D printing or additive manufacturing is the construction of a three-dimensional object from a CAD model or a digital 3D model. It can be done in a variety of processes in which material is deposited, joined or solidified under computer control, with material being added together (such as plastics, liquids or powder grains being fused), typically layer by layer. In the 1980s, 3D printing techniques were considered suitable only for the production of functional or aesthetic prototypes, and a more appropriate term for it at the time was rapid prototyping.

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