Lecture

A model of cortical propagating waves

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Description

This lecture by Alain Destexhe presents a model of cortical propagating waves in the brain, focusing on the network of AI-state units, connectivity profiles, inhibition, and excitation. The lecture discusses the interaction between stimuli, response to apparent motion, and suppression mechanisms. Destexhe explains how the VSD signal is proportional to the subthreshold Vm of cortical cells, highlighting the inhibitory activity's impact on excitatory activity. The model obtained from the study displays propagating waves and their suppressive effects, providing insights into the conductance-based interactions between individual neurons.

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Gamma wave

A gamma wave or gamma rhythm is a pattern of neural oscillation in humans with a frequency between 25 and 140 Hz, the 40 Hz point being of particular interest. Gamma rhythms are correlated with large scale brain network activity and cognitive phenomena such as working memory, attention, and perceptual grouping, and can be increased in amplitude via meditation or neurostimulation. Altered gamma activity has been observed in many mood and cognitive disorders such as Alzheimer's disease, epilepsy, and schizophrenia.

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Alpha waves, or the alpha rhythm, are neural oscillations in the frequency range of 8–12 Hz likely originating from the synchronous and coherent (in phase or constructive) electrical activity of thalamic pacemaker cells in humans. Historically, they are also called "Berger's waves" after Hans Berger, who first described them when he invented the EEG in 1924. Alpha waves are one type of brain waves detected by electrophysiological and closely related methods, such as by electroencephalography (EEG) or magnetoencephalography (MEG), and can be quantified using quantitative electroencephalography (qEEG).

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Brain simulation is the concept of creating a functioning computer model of a brain or part of a brain. Brain simulation projects intend to contribute to a complete understanding of the brain, and eventually also assist the process of treating and diagnosing brain diseases. Various simulations from around the world have been fully or partially released as open source software, such as C. elegans, and the Blue Brain Project Showcase.

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Large-scale brain networks (also known as intrinsic brain networks) are collections of widespread brain regions showing functional connectivity by statistical analysis of the fMRI BOLD signal or other recording methods such as EEG, PET and MEG. An emerging paradigm in neuroscience is that cognitive tasks are performed not by individual brain regions working in isolation but by networks consisting of several discrete brain regions that are said to be "functionally connected".

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