BIBO stabilityIn signal processing, specifically control theory, bounded-input, bounded-output (BIBO) stability is a form of stability for signals and systems that take inputs. If a system is BIBO stable, then the output will be bounded for every input to the system that is bounded. A signal is bounded if there is a finite value such that the signal magnitude never exceeds , that is For discrete-time signals: For continuous-time signals: For a continuous time linear time-invariant (LTI) system, the condition for BIBO stability is that the impulse response, , be absolutely integrable, i.
FeedbackFeedback occurs when outputs of a system are routed back as inputs as part of a chain of cause-and-effect that forms a circuit or loop. The system can then be said to feed back into itself. The notion of cause-and-effect has to be handled carefully when applied to feedback systems: Simple causal reasoning about a feedback system is difficult because the first system influences the second and second system influences the first, leading to a circular argument.
Negative feedbackNegative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances. Whereas positive feedback tends to lead to instability via exponential growth, oscillation or chaotic behavior, negative feedback generally promotes stability. Negative feedback tends to promote a settling to equilibrium, and reduces the effects of perturbations.
CyclinCyclin is a family of proteins that controls the progression of a cell through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes or group of enzymes required for synthesis of cell cycle. Cyclins were originally discovered by R. Timothy Hunt in 1982 while studying the cell cycle of sea urchins. In an interview for "The Life Scientific" (aired on 13/12/2011) hosted by Jim Al-Khalili, R. Timothy Hunt explained that the name "cyclin" was originally named after his hobby cycling.
Cdc25Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle proteins or genes such as Cdc2 and Cdc4, the "cdc" in its name refers to "cell division control". Dual-specificity phosphatases are considered a sub-class of protein tyrosine phosphatases. By removing inhibitory phosphate residues from target cyclin-dependent kinases (Cdks), Cdc25 proteins control entry into and progression through various phases of the cell cycle, including mitosis and S ("Synthesis") phase.
G2 phaseDISPLAYTITLE:G2 phase G2 phase, Gap 2 phase, or Growth 2 phase, is the third subphase of interphase in the cell cycle directly preceding mitosis. It follows the successful completion of S phase, during which the cell’s DNA is replicated. G2 phase ends with the onset of prophase, the first phase of mitosis in which the cell’s chromatin condenses into chromosomes. G2 phase is a period of rapid cell growth and protein synthesis during which the cell prepares itself for mitosis.
Slope stabilitySlope stability refers to the condition of inclined soil or rock slopes to withstand or undergo movement; the opposite condition is called slope instability or slope failure. The stability condition of slopes is a subject of study and research in soil mechanics, geotechnical engineering and engineering geology. Analyses are generally aimed at understanding the causes of an occurred slope failure, or the factors that can potentially trigger a slope movement, resulting in a landslide, as well as at preventing the initiation of such movement, slowing it down or arresting it through mitigation countermeasures.
Slope stability analysisSlope stability analysis is a static or dynamic, analytical or empirical method to evaluate the stability of slopes of soil- and rock-fill dams, embankments, excavated slopes, and natural slopes in soil and rock. It is performed to assess the safe design of a human-made or natural slopes (e.g. embankments, road cuts, open-pit mining, excavations, landfills etc.) and the equilibrium conditions. Slope stability is the resistance of inclined surface to failure by sliding or collapsing.
Cyclin BCyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). The complex of Cdk and cyclin B is called maturation promoting factor or mitosis promoting factor (MPF). Cyclin B is necessary for the progression of the cells into and out of M phase of the cell cycle.
Climate change feedbackClimate change feedbacks are effects of global warming that amplify or diminish the effect of forces that initially cause the warming. Positive feedbacks enhance global warming while negative feedbacks weaken it. Feedbacks are important in the understanding of climate change because they play an important part in determining the sensitivity of the climate to warming forces. Climate forcings and feedbacks together determine how much and how fast the climate changes.
BistabilityIn a dynamical system, bistability means the system has two stable equilibrium states. A bistable structure can be resting in either of two states. An example of a mechanical device which is bistable is a light switch. The switch lever is designed to rest in the "on" or "off" position, but not between the two. Bistable behavior can occur in mechanical linkages, electronic circuits, nonlinear optical systems, chemical reactions, and physiological and biological systems.
Cyclin ECyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle that determines initiation of DNA duplication. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase. Like all cyclin family members, cyclin E forms a complex with cyclin-dependent kinase (CDK2).
