Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Pharmacokinetic & Pharmacodynamic Evaluations

Related lectures (32)

Pharmacokinetics: Drug Absorption and Distribution

Explores drug absorption, distribution, and clinical implications, focusing on salicylate poisoning and drug trapping in lysosomes.

Pharmacokinetics Modeling: Zero and First-Order Kinetics

Explores pharmacokinetics modeling, covering zero and first-order kinetics, drug distribution, and key parameters for drug elimination.

Interrogating Drugs' Mode of Action

Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.

Peptide Therapeutics

Explores the development and advantages of peptide therapeutics, including conversion into peptidomimetics and solid phase peptide synthesis.

Drug Metabolism: Xenobiotics and Enzymes

Explores drug metabolism, focusing on xenobiotics, enzymes, biotransformation reactions, and factors affecting drug metabolism.

Drug Development and Ethical Principles

Explores the historical aspects of drug development, regulatory agencies, and ethical principles in pharmacology, emphasizing the importance of informed consent and human subject protection.

Pharmacogenetics: Drug Response and Genetic Variability

Delves into pharmacogenetics, exploring genetic influences on drug response variability and metabolism.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Preclinical Update: Regulatory Guidelines & Dose Determination

Discusses regulatory guidelines, dose determination, risk mitigation in FIH trials, and considerations for ascending doses.

Drug Targets: Adrenergic Signaling

Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.

Pharmacodynamics: Ligand Concentration, Binding, and Effect

Explores the relationship between ligand concentration, binding, and effect, focusing on allosteric modulators and types of pharmacological antagonists.

Drug Development and Regulations: Europe

Explores drug development and regulations in Europe, focusing on clinical trials, regulatory frameworks, and marketing authorization procedures.

Selective Drug Targeting Mechanisms

Explores selective drug targeting mechanisms, resistance development, tuberculosis incidence, BCR-ABL mutations, tyrosine kinase inhibitors, drug toxicity, interactions, and toxicology studies.

Immunoediting of Tumors: Experimental Evidence and Mechanisms

Explores tumor immunoediting, mechanisms of tumor escape, and cancer immunotherapy, emphasizing immune response regulation and recent drug approvals.

Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

Regulation of Therapeutic Products

Explores the regulation of therapeutic products, covering legal requirements, product classification, market access, and advertising rules.

Small Molecule Drugs: Cardiovascular Diseases

Explores the molecular basis and treatment of cardiovascular diseases, focusing on atherosclerosis, hypertension, and drug therapies.

Frontiers in Chemical Biology

Explores the druggable proteome, PROTACS strategy, ubiquitin attachment, and drug development paradigms.

Protein Therapeutics: Blood Proteins and Enzymes

Explores blood composition, proteins, coagulation, diseases treated with enzymes, and case studies on genetic disorders.

Kidney-on-a-Chip Technologies

Covers the state-of-the-art kidney-on-chip technologies aiming to facilitate pharmaceutical research and eliminate animal testing.