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This lecture explores the causes and challenges of cybersickness in virtual reality (VR) environments, focusing on the perceptual conflict theory. It covers common triggers like motion sickness, accommodation-vergence conflict, and latency issues, emphasizing the importance of user safety in VR application design. The main cause of cybersickness is the conflict between the vestibular system and visually perceived movement, leading to symptoms such as disequilibrium, fatigue, nausea, and vertigo.