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This lecture covers the concepts of cyclic deformation and fatigue, which are responsible for a significant percentage of mechanical engineering failures. It explains the factors influencing fatigue behavior, S-N curves, and the effects of stress on fatigue life. The presentation also delves into the accumulation of plastic deformation, stress-controlled vs. strain-controlled conditions, and the different stages of creep. Practical exercises involve calculating fatigue life for various stress amplitudes and predicting remaining lifetime under cyclic stresses. Additionally, the lecture explores the impact of factors like notch presence, surface roughness, sample diameter, and loading type on fatigue behavior.