Electrospray ionizationElectrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules because it overcomes the propensity of these molecules to fragment when ionized. ESI is different from other ionization processes (e.g. matrix-assisted laser desorption/ionization (MALDI)) since it may produce multiple-charged ions, effectively extending the mass range of the analyser to accommodate the kDa-MDa orders of magnitude observed in proteins and their associated polypeptide fragments.
Weakly interacting massive particleWeakly interacting massive particles (WIMPs) are hypothetical particles that are one of the proposed candidates for dark matter. There exists no formal definition of a WIMP, but broadly, it is a new elementary particle which interacts via gravity and any other force (or forces), potentially not part of the Standard Model itself, which is as weak as or weaker than the weak nuclear force, but also non-vanishing in its strength.
Accelerator physicsAccelerator physics is a branch of applied physics, concerned with designing, building and operating particle accelerators. As such, it can be described as the study of motion, manipulation and observation of relativistic charged particle beams and their interaction with accelerator structures by electromagnetic fields. It is also related to other fields: Microwave engineering (for acceleration/deflection structures in the radio frequency range). Optics with an emphasis on geometrical optics (beam focusing and bending) and laser physics (laser-particle interaction).
Liquid scintillation countingLiquid scintillation counting is the measurement of radioactive activity of a sample material which uses the technique of mixing the active material with a liquid scintillator (e.g. zinc sulfide), and counting the resultant photon emissions. The purpose is to allow more efficient counting due to the intimate contact of the activity with the scintillator. It is generally used for alpha particle or beta particle detection.
Electron ionizationElectron ionization (EI, formerly known as electron impact ionization and electron bombardment ionization) is an ionization method in which energetic electrons interact with solid or gas phase atoms or molecules to produce ions. EI was one of the first ionization techniques developed for mass spectrometry. However, this method is still a popular ionization technique. This technique is considered a hard (high fragmentation) ionization method, since it uses highly energetic electrons to produce ions.
ParticleIn the physical sciences, a particle (or corpuscule in older texts) is a small localized object which can be described by several physical or chemical properties, such as volume, density, or mass. They vary greatly in size or quantity, from subatomic particles like the electron, to microscopic particles like atoms and molecules, to macroscopic particles like powders and other granular materials. Particles can also be used to create scientific models of even larger objects depending on their density, such as humans moving in a crowd or celestial bodies in motion.
Lightest supersymmetric particleIn particle physics, the lightest supersymmetric particle (LSP) is the generic name given to the lightest of the additional hypothetical particles found in supersymmetric models. In models with R-parity conservation, the LSP is stable; in other words, it cannot decay into any Standard Model particle, since all SM particles have the opposite R-parity. There is extensive observational evidence for an additional component of the matter density in the universe, which goes under the name dark matter.
Wave–particle dualityWave–particle duality is the concept in quantum mechanics that quantum entities exhibit both particle and a wave properties according to the experimental circumstances. It expresses the inability of the classical concepts "particle" or "wave" to fully describe the behaviour of quantum-scale objects. As Albert Einstein wrote: It seems as though we must use sometimes the one theory and sometimes the other, while at times we may use either. We are faced with a new kind of difficulty.
Particle decayIn particle physics, particle decay is the spontaneous process of one unstable subatomic particle transforming into multiple other particles. The particles created in this process (the final state) must each be less massive than the original, although the total invariant mass of the system must be conserved. A particle is unstable if there is at least one allowed final state that it can decay into. Unstable particles will often have multiple ways of decaying, each with its own associated probability.
Double beta decayIn nuclear physics, double beta decay is a type of radioactive decay in which two neutrons are simultaneously transformed into two protons, or vice versa, inside an atomic nucleus. As in single beta decay, this process allows the atom to move closer to the optimal ratio of protons and neutrons. As a result of this transformation, the nucleus emits two detectable beta particles, which are electrons or positrons. The literature distinguishes between two types of double beta decay: ordinary double beta decay and neutrinoless double beta decay.
Particle acceleratorA particle accelerator is a machine that uses electromagnetic fields to propel charged particles to very high speeds and energies, and to contain them in well-defined beams. Large accelerators are used for fundamental research in particle physics. The largest accelerator currently active is the Large Hadron Collider (LHC) near Geneva, Switzerland, operated by the CERN. It is a collider accelerator, which can accelerate two beams of protons to an energy of 6.5 TeV and cause them to collide head-on, creating center-of-mass energies of 13 TeV.
Charged particleIn physics, a charged particle is a particle with an electric charge. It may be an ion, such as a molecule or atom with a surplus or deficit of electrons relative to protons. It can also be an electron or a proton, or another elementary particle, which are all believed to have the same charge (except antimatter). Another charged particle may be an atomic nucleus devoid of electrons, such as an alpha particle. A plasma is a collection of charged particles, atomic nuclei and separated electrons, but can also be a gas containing a significant proportion of charged particles.
